Savtsova Z D, Kovbasiuk S A, Iudina O Iu, Zaritskaia M Iu, Voeĭkova I M, Orlovskiĭ A A, Indyk V M, Serkiz Ia I
Radiobiologiia. 1991 Sep-Oct;31(5):687-93.
The immune status of mice has been assessed by the whole complex of data. The permanent action of low-level radiation has been shown to suppress considerably the rate of reactions of the delayed-type hypersensitivity and "graft versus host" disease, as well as NK and specific cytolytic T-lymphocyte activity. The dynamics of accumulation and the levels of antiviral antibodies in the serum, lung and trachea extracts are virtually invariable. The resistance of experimental animals to influenza is lower than that of non-irradiated mice of the same line and age. The data obtained indicate that the immune disturbances revealed are connected not only with the alteration of lymphoid cell populations, but also with the alteration of the immune regulation mechanisms.
通过一系列综合数据评估了小鼠的免疫状态。结果表明，低水平辐射的长期作用会显著抑制迟发型超敏反应和“移植物抗宿主”病的反应率，以及自然杀伤细胞（NK）和特异性细胞毒性T淋巴细胞的活性。血清、肺和气管提取物中抗病毒抗体的积累动态和水平实际上没有变化。实验动物对流感的抵抗力低于同品系和年龄的未辐照小鼠。所获得的数据表明，所揭示的免疫紊乱不仅与淋巴细胞群体的改变有关，还与免疫调节机制的改变有关。
