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[切尔诺贝利原子能发电站事故对动物的生物学影响。11. 不同代大鼠骨髓细胞的超微结构]

[The biological effects in animals in relation to the accident at the Chernobyl Atomic Electric Power Station. 11. The ultrastructure of the bone marrow cells in different generations of rats].

作者信息

Afanas'eva V V, Zak K P, Indyk V M, Serkiz Ia I, Tron'ko N D

出版信息

Radiobiologiia. 1991 Sep-Oct;31(5):694-700.

PMID:1745758
Abstract

In studying the bone marrow cell ultrastructure in male rats (F0-F2 generations) aged 3 months, which were brought up within the thirty kilometer Chernobyl A.P.S. disaster area, considerable submicroscopic changes have been revealed in the cells at all stages of maturation, including undifferentiated blasts and mature forms of cells of the neutrophilic, eosinophilic, monocytic and erythroid haemopoiesis series, as well as stromal elements of the microenvironment, megakaryocytes and endothelium. The severity of these changes increases, as the number of generations grows, displaying frequently a destructive character.

摘要

在对3个月大的雄性大鼠(F0 - F2代)的骨髓细胞超微结构进行研究时,这些大鼠是在切尔诺贝利原子能电站事故区域30公里范围内饲养的,结果发现在细胞成熟的各个阶段都有相当大的亚微观变化,包括未分化的原始细胞以及嗜中性、嗜酸性、单核细胞和红细胞造血系列细胞的成熟形式,还有微环境的基质成分、巨核细胞和内皮细胞。随着代数的增加,这些变化的严重程度会加剧,且常常呈现出破坏性特征。

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