Pérez Arellano J L, Ramos Guevara R M, López Ochoa F J, Alcázar Montero M C, de León Gómez B, Flores M T, Luna Rodrigo G
Departamento de Medicina, Hospital Clínico Universitario, Salamanca.
Rev Clin Esp. 1991 Sep;189(4):159-62.
Sarcoidosis is a disease which presents important clinical differences according to its geographical distribution. Thus, the objective of this study was to evaluate the epidemiologic, clinical, radiologic, and diagnostic characteristics in a series of 30 sarcoidosis patients in the province of Salamanca (representing the Castilla-Leon region). The most relevant results are the following: a) in our region, sarcoidosis predominates in females and furthermore, the presenting age in females is greater than in males; b) there is a clear predominance of the disease in the rural area; c) the prevalence of smoking habit in these patients is low (10%); d) the clinical manifestations are similar to other Spanish series with the exception, however of a high incidence of hypercalciuria; e) there is no correlation between the increase in sedimentation rate and the degree of sarcoidosis activity; f) there is a predominance of the radiologic type 11 of the disease and there is a high number of atypic radiologic patterns. The results obtained are with regard to the pathogeny are discussed as well as the differences and similarities of this series with other preceding from other regions.
结节病是一种根据地理分布呈现出重要临床差异的疾病。因此,本研究的目的是评估萨拉曼卡省(代表卡斯蒂利亚-莱昂地区)的30例结节病患者的流行病学、临床、放射学和诊断特征。最相关的结果如下:a)在我们地区,结节病在女性中更为常见,而且女性的发病年龄大于男性;b)该病在农村地区明显更为普遍;c)这些患者中吸烟习惯的患病率较低(10%);d)临床表现与其他西班牙系列相似,但高钙尿症的发生率除外;e)血沉升高与结节病活动程度之间没有相关性;f)该病的放射学类型11占主导,且非典型放射学模式数量较多。讨论了所获得的关于病因的结果,以及该系列与其他地区先前系列的差异和相似之处。