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自体骨和富血小板血浆(PRP)治疗骨内缺损

Autogenous bone and platelet-rich plasma (PRP) in the treatment of intrabony defects.

作者信息

Czuryszkiewicz-Cyrana J, Banach J

机构信息

Department of Parodontology, Pomeranian Medical University in Szczecin, Poland.

出版信息

Adv Med Sci. 2006;51 Suppl 1:26-30.

PMID:17458055
Abstract

PURPOSE

Obtaining an answer to the question whether autogenous bone in combination with PRP give a therapeutical effect in the form of periodontal ligament attachment regeneration. Defining the degree of elimination of a convenient environment for subgingival bacterial plaque by reduction of periodontal pocket depth and periodontitis.

MATERIAL AND METHODS

Twenty-six systematically healthy patients with diagnosed chronic and advanced periodontitis (24 females and 2 males) were selected for the study. In general 72 periodontal infrabony pockets were treated. Clinically the following indexes were examined and measured: 1. Plaque Index by Silness and Löe. 2. Sulcus Bleeding Index by Mühlemann and Son. 3. Clinical Attachment Level (mm). 4. Pocket Depth (mm). 5. Gingival Recession (mm). 6. Tooth mobility with the use of Periotest. 7. Degree of alveolar bone loss with the use of Engelberger, Marthaler and Rateitschak index - EMR Index.

RESULTS

At 12 months after treatment the following results were noted: Mean value of attachment level regeneration 3.47 mm. Mean value of pocket depth decreased by 3.7 mm. Mean value of tooth mobility reduction by 48.3%. Megeneration of alveolar bone by 9.24%.

CONCLUSIONS

  1. Autogenous bone with added PRP in treatment of intrabony defects caused by periodontitis have given significant clinical improvement of the periodontal tissues. 2. The combination of PRP and autogenous bone caused the elimination of a convenient environment for subgingival bacterial plaque eliminating periodontitis.
摘要

目的

探究自体骨联合富血小板血浆(PRP)是否能实现牙周韧带附着再生的治疗效果。通过减少牙周袋深度和牙周炎来确定消除龈下菌斑适宜环境的程度。

材料与方法

选取26例经系统检查健康、诊断为慢性重度牙周炎的患者(24例女性,2例男性)进行研究。共治疗72个牙周骨下袋。临床检查并测量以下指标:1. 采用Silness和Löe的菌斑指数。2. 采用Mühlemann和Son的龈沟出血指数。3. 临床附着水平(mm)。4. 牙周袋深度(mm)。5. 牙龈退缩(mm)。6. 使用Periotest测量牙齿松动度。7. 使用恩格尔伯格、马特勒和拉特沙克指数(EMR指数)测量牙槽骨吸收程度。

结果

治疗12个月后观察到以下结果:附着水平再生的平均值为3.47 mm。牙周袋深度平均值减少3.7 mm。牙齿松动度平均值降低48.3%。牙槽骨再生9.24%。

结论

  1. 自体骨联合PRP治疗牙周炎引起的骨内缺损可显著改善牙周组织的临床状况。2. PRP与自体骨的联合使用消除了龈下菌斑的适宜环境,从而消除了牙周炎。

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