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血小板浓缩物和生长因子在面部年轻化中的作用：一项病例系列的系统评价

The Role of Platelet Concentrates and Growth Factors in Facial Rejuvenation: A Systematic Review with Case Series.

作者信息

Malcangi Giuseppina, Inchingolo Angelo Michele, Inchingolo Alessio Danilo, Ferrante Laura, Latini Giulia, Trilli Irma, Nardelli Paola, Longo Marialuisa, Palermo Andrea, Inchingolo Francesco, Dipalma Gianna

机构信息

Department of Interdisciplinary Medicine, University of Bari "Aldo Moro", 70124 Bari, Italy.

Department of Experimental Medicine, University of Salento, 73100 Lecce, Italy.

出版信息

Medicina (Kaunas). 2025 Jan 7;61(1):84. doi: 10.3390/medicina61010084.

DOI:10.3390/medicina61010084
PMID:39859067
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11767021/
Abstract

: Due to the regeneration potential of growth factors (GFs) and platelet concentrates (PCs), facial rejuvenation has been a major area of attention in esthetic medicine. The effectiveness and safety of PCs and GFs in promoting face rejuvenation are examined in this systematic review, which is complemented by a case series. GFs are essential for collagen production and dermal matrix remodeling, while PCs, like Platelet-Rich Plasma (PRP), are abundant in bioactive chemicals that promote tissue healing and cellular regeneration. : A comprehensive literature search was performed on PubMed, Web of Science, and Scopus, focusing on human clinical trials published between February 2019 and February 2024 related to PRP and facial esthetics. : Thirteen studies met the inclusion criteria and were analyzed. : The review summarizes the most recent data on patient outcomes, treatment regimens, and possible hazards. The case series that goes with it shows real-world examples of how to improve skin elasticity, texture, and general facial appearance with little negative side effects. These results highlight the potential use of PCs and GFs as minimally invasive procedures.

摘要

由于生长因子（GFs）和血小板浓缩物（PCs）具有再生潜力，面部年轻化一直是美容医学关注的主要领域。本系统评价结合病例系列研究，探讨了PCs和GFs促进面部年轻化的有效性和安全性。GFs对胶原蛋白生成和真皮基质重塑至关重要，而PCs，如富含血小板血浆（PRP），富含促进组织愈合和细胞再生的生物活性化学物质。：在PubMed、科学网和Scopus上进行了全面的文献检索，重点关注2019年2月至2024年2月间发表的与PRP和面部美学相关的人体临床试验。：13项研究符合纳入标准并进行了分析。：该综述总结了关于患者预后、治疗方案和可能风险的最新数据。与之配套的病例系列展示了在几乎没有负面副作用的情况下改善皮肤弹性、质地和整体面部外观的真实案例。这些结果突出了PCs和GFs作为微创程序的潜在用途。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6c7c/11767021/0fc891c173a8/medicina-61-00084-g009a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6c7c/11767021/870df2932934/medicina-61-00084-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6c7c/11767021/53645ce7b369/medicina-61-00084-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6c7c/11767021/fb55cf180bb8/medicina-61-00084-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6c7c/11767021/d3116455ef98/medicina-61-00084-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6c7c/11767021/849b69c42406/medicina-61-00084-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6c7c/11767021/cfb12fce2239/medicina-61-00084-g006a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6c7c/11767021/710f991e0010/medicina-61-00084-g007a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6c7c/11767021/0f70284cca06/medicina-61-00084-g008a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6c7c/11767021/0fc891c173a8/medicina-61-00084-g009a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6c7c/11767021/870df2932934/medicina-61-00084-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6c7c/11767021/53645ce7b369/medicina-61-00084-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6c7c/11767021/fb55cf180bb8/medicina-61-00084-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6c7c/11767021/d3116455ef98/medicina-61-00084-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6c7c/11767021/849b69c42406/medicina-61-00084-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6c7c/11767021/cfb12fce2239/medicina-61-00084-g006a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6c7c/11767021/710f991e0010/medicina-61-00084-g007a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6c7c/11767021/0f70284cca06/medicina-61-00084-g008a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6c7c/11767021/0fc891c173a8/medicina-61-00084-g009a.jpg

相似文献

[1]
The Role of Platelet Concentrates and Growth Factors in Facial Rejuvenation: A Systematic Review with Case Series.

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[2]
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[3]
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引用本文的文献

[1]
Regenerative potential of PRP-based scaffolds in chronic wound healing: Mechanisms, advances, and therapeutic insights.

Regen Ther. 2025-6-26

[2]
Platelet-rich plasma intra-plaque injections rapidly reduce penile curvature and improve sexual function in Peyronie's disease patients: results from a prospective large-cohort study.

World J Urol. 2025-5-15

本文引用的文献

[1]
The Well-Forgotten Old: Platelet-Rich Plasma in Modern Anti-Aging Therapy.

Cells. 2024-10-23

[2]
Efficacy and safety of allogeneic platelet-rich plasma in chronic wound treatment: a meta-analysis of randomized controlled trials.

Sci Rep. 2024-10-24

[3]
Survival Mechanisms and Retention Strategies in Large-Volume Fat Grafting: A Comprehensive Review and Future Perspectives.

Aesthetic Plast Surg. 2024-10

[4]
Current Challenges in the Development of Platelet-Rich Plasma-Based Therapies.

Biomed Res Int. 2024

[5]
Informed consent form for platelet rich plasma injections: evidence-based and legally guide for orthopaedic surgeons.

Eur J Med Res. 2024-8-17

[6]
Bidirectional Association between Periodontitis and Thyroid Disease: A Scoping Review.

Int J Environ Res Public Health. 2024-6-30

[7]
Effect of Health Status and Heat-Induced Inactivation on the Proteomic Profile of Plasma Rich in Growth Factors Obtained from Donors with Chronic Inflammatory Skin Conditions.

Biomolecules. 2024-6-26

[8]
Difference in the Intestinal Microbiota between Breastfeed Infants and Infants Fed with Artificial Milk: A Systematic Review.

Pathogens. 2024-6-24

[9]
Therapeutic Strategies and Genetic Implications for Periodontal Disease Management: A Systematic Review.

Int J Mol Sci. 2024-6-29

[10]
The Role of Curcumin in Oral Health and Diseases: A Systematic Review.

Antioxidants (Basel). 2024-5-28

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