Mathur Ashish, Bains Vivek Kumar, Gupta Vivek, Jhingran Rajesh, Singh G P
Department of Periodontology, Saraswati Dental College, Lucknow, Uttar Pradesh, India.
Rama Dental College Hospital and Research Centre, Kanpur, Uttar Pradesh, India.
Eur J Dent. 2015 Jan-Mar;9(1):100-108. doi: 10.4103/1305-7456.149653.
The primary objective of this study was to compare clinically and radiographically the efficacy of autologous platelet rich fibrin (PRF) and autogenous bone graft (ABG) obtained using bone scrapper in the treatment of intrabony periodontal defects.
Thirty-eight intrabony defects (IBDs) were treated with either open flap debridement (OFD) with PRF or OFD with ABG. Clinical parameters were recorded at baseline and 6 months postoperatively. The defect-fill and defect resolution at baseline and 6 months were calculated radiographically (intraoral periapical radiographs [IOPA] and orthopantomogram [OPG]).
Significant probing pocket depth (PPD) reduction, clinical attachment level (CAL) gain, defect fill and defect resolution at both PRF and ABG treated sites with OFD was observed. However, inter-group comparison was non-significant (P > 0.05). The bivariate correlation results revealed that any of the two radiographic techniques (IOPA and OPG) can be used for analysis of the regenerative therapy in IBDs.
The use of either PRF or ABG were effective in the treatment of three wall IBDs with an uneventful healing of the sites.
本研究的主要目的是从临床和影像学方面比较自体富血小板纤维蛋白（PRF）和使用骨刮匙获取的自体骨移植（ABG）治疗骨内牙周缺损的疗效。
38例骨内缺损（IBD）患者接受了用PRF的开放瓣清创术（OFD）或用ABG的OFD治疗。在基线和术后6个月记录临床参数。通过影像学方法（口腔根尖片[IOPA]和曲面断层片[OPG]）计算基线和6个月时的缺损填充和缺损修复情况。
观察到在接受OFD治疗的PRF和ABG治疗部位，探诊深度（PPD）显著降低，临床附着水平（CAL）增加，缺损填充和缺损修复。然而，组间比较无显著差异（P>0.05）。双变量相关性结果显示，两种影像学技术（IOPA和OPG）中的任何一种均可用于分析IBDs的再生治疗。
使用PRF或ABG治疗三壁IBDs均有效，且治疗部位愈合良好。
