迟发性弥漫性板层角膜炎
Late-onset diffuse lamellar keratitis.
作者信息
Amano Rie, Ohno Koji, Shimizu Kimiya, Suzuki Masanobu, Aizawa Daisuke, Komatsu Mari
机构信息
Department of Ophthalmology, Kitasato University, Kanagawa, Japan.
出版信息
Jpn J Ophthalmol. 2003 Sep-Oct;47(5):463-8. doi: 10.1016/s0021-5155(03)00102-3.
BACKGROUND
Diffuse lamellar keratitis (DLK) is marked by the presence of diffuse or multifocal infiltrates confined to the laser in situ keratomileusis (LASIK) interface. These infiltrates are culture-negative, and the etiology is thought to be noninfectious. Most cases of DLK occur within the first week or 2 following surgery.
CASES
We described 2 cases of DLK that occurred 3 months after LASIK. These patients were treated with intensive topical corticosteroids.
RESULTS
Treatment with topical corticosteroid was instituted, with rapid improvement in patient symptoms, visual acuity, and slit-lamp biomicroscopic findings.
CONCLUSION
DLK may occur as late as 3 months after LASIK.
背景
弥漫性板层角膜炎（DLK）的特征是局限于准分子原位角膜磨镶术（LASIK）界面的弥漫性或多灶性浸润。这些浸润培养阴性，病因被认为是非感染性的。大多数DLK病例发生在术后第一周或第二周内。
病例
我们描述了2例LASIK术后3个月发生的DLK病例。这些患者接受了强化局部皮质类固醇治疗。
结果
采用局部皮质类固醇治疗，患者症状、视力和裂隙灯生物显微镜检查结果迅速改善。
结论
DLK可能在LASIK术后长达3个月时发生。
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