Hyldegaard O, Møller M, Madsen J
Institute of Medical Physiology C, University of Copenhagen, Denmark.
Undersea Biomed Res. 1991 Sep-Nov;18(5-6):361-71.
Injected air bubbles in spinal white matter in the rat were studied at 1 bar after decompression from an exposure to air at 3.1 bar (absolute) for 4 h. During air breathing all injected bubbles grew for the first 2 h of the observation period. Thereafter three of nine bubbles began to shrink and one of them disappeared. During breathing of heliox (80:20) bubbles consistently shrank and disappeared from view. If the breathing gas was changed from heliox to N2O-O2 (80:20), while bubbles still had an appreciable size, they started growing again. If the change to N2O-O2 was done after a bubble disappeared from view, it did not reappear. During breathing of 100% oxygen, all bubbles initially grew. Subsequently they all shrank and disappeared at about the same time after gas shift, as during heliox breathing. The effect of heliox treatment on CNS decompression sickness after air dives is discussed.
在大鼠身上，研究了在从3.1巴（绝对压力）暴露于空气4小时后减压至1巴时脊髓白质中注入的气泡。在空气呼吸期间，所有注入的气泡在观察期的前2小时都在增大。此后，九个气泡中有三个开始缩小，其中一个消失。在呼吸氦氧混合气（80:20）时，气泡持续缩小并从视野中消失。如果呼吸气体从氦氧混合气改为一氧化二氮-氧气（80:20），而气泡仍有可观的大小，它们会再次开始增大。如果在气泡从视野中消失后改为一氧化二氮-氧气，气泡不会再次出现。在呼吸100%氧气时，所有气泡最初都会增大。随后，它们都会缩小，并在气体转换后大约同时消失，与呼吸氦氧混合气时一样。讨论了氦氧混合气治疗对空气潜水后中枢神经系统减压病的影响。
