Hyldegaard O, Madsen J
Institute of Medical Physiology C, University of Copenhagen, Denmark.
Undersea Biomed Res. 1989 May;16(3):185-93.
Bubbles in rat adipose tissue were studied at 1 bar after decompression from an exposure to air at 3.3 bars (absolute) for 4 h. During air breathing the bubbles grew throughout the observation period. During heliox (80:20) breathing they shrank and eventually disappeared from view. If the breathing gas was changed from heliox back to air or to N2O-O2 (80:20) while the bubbles still had an appreciable size, they started growing again. If the change to N2O was done after or a few minutes before a bubble disappeared from view, it did not reappear. During breathing of 100% O2, most bubbles containing N2 initially grew and then maintained their size for a while before diminishing. However, some bubbles did not start shrinking during the 2-3-h observation period. The relevance of the findings to heliox treatment of CNS decompression sickness after air dives is discussed.
在从3.3巴（绝对压力）的空气暴露中减压4小时后，在1巴压力下对大鼠脂肪组织中的气泡进行了研究。在空气呼吸期间，气泡在整个观察期内都在生长。在氦氧混合气（80:20）呼吸期间，它们会收缩并最终从视野中消失。如果在气泡仍有明显大小时，将呼吸气体从氦氧混合气换回空气或换成一氧化二氮 - 氧气（80:20），它们会再次开始生长。如果在气泡从视野中消失后或消失前几分钟换成一氧化二氮，气泡不会再次出现。在100%氧气呼吸期间，大多数含有氮气的气泡最初会生长，然后在一段时间内保持其大小，之后才会减小。然而，在2 - 3小时的观察期内，一些气泡并没有开始收缩。讨论了这些发现与空气潜水后中枢神经系统减压病的氦氧混合气治疗的相关性。
