el-Naggar A, Ro J Y, Sella A, Ayala A G
Department of Pathology, University of Texas M.D. Anderson Cancer Center, Houston.
Urology. 1991 Dec;38(6):585-8. doi: 10.1016/0090-4295(91)80186-b.
We report the DNA content in simultaneous renal and papillary transitional cell carcinomas in the same kidney with a subsequent metastasis of the transitional cell carcinoma to a left supraclavicular lymph node. The flow cytometric DNA analysis revealed aneuploid stemlines with identical DNA indices in both the transitional cell carcinoma and the metastatic lesion and a diploid pattern in the renal cell carcinoma. A discussion of these findings and the potential implication of DNA ploidy analysis in similar situations is presented.
我们报告了同一肾脏中同时发生的肾和乳头状移行细胞癌的DNA含量，随后该移行细胞癌转移至左锁骨上淋巴结。流式细胞术DNA分析显示，移行细胞癌及其转移灶中均存在非整倍体干细胞系且DNA指数相同，而肾细胞癌呈二倍体模式。本文对这些发现以及DNA倍体分析在类似情况下的潜在意义进行了讨论。
