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美国男男性行为者中艾滋病毒流行率和疾病进展方面的种族/族裔及年龄差异。

Racial/ethnic and age disparities in HIV prevalence and disease progression among men who have sex with men in the United States.

作者信息

Hall H Irene, Byers Robert H, Ling Qiang, Espinoza Lorena

机构信息

Division of HIV/AIDS Prevention, National Center for HIV, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, Ga 30333, USA.

出版信息

Am J Public Health. 2007 Jun;97(6):1060-6. doi: 10.2105/AJPH.2006.087551. Epub 2007 Apr 26.

Abstract

OBJECTIVES

We examined HIV diagnosis rates and disease progression among men who have sex with men (MSM) according to race/ethnicity and age.

METHODS

Using data obtained from the national HIV/AIDS surveillance system, we examined trends in HIV diagnosis rates for 2001 through 2004 using Poisson regression. We used a standardized Kaplan-Meier method to determine differences in time of progression from HIV to AIDS and AIDS survival.

RESULTS

HIV diagnosis rates were higher for Black and Hispanic than for White MSM, but trends within age groups from 2001 to 2004 did not differ by race/ethnicity. Diagnosis rates increased among MSM aged 13 to 19 years (14% per year), 20 to 24 years (13%), 25 to 29 years, and 40 to 54 years (3%-6%; P< or = .01 for each). The percentage of MSM who did not have AIDS 3 years after HIV diagnosis was lower among Black (66.8%; 95% confidence interval [CI]=66.1, 67.4) and Hispanic (68.1%; 95% CI=67.5, 68.8) than among White MSM (74.7%; 95% CI=74.2, 75.1). Three-year survival after AIDS diagnosis was lower for Black than for White or Hispanic MSM.

CONCLUSIONS

HIV prevention efforts should target young and middle-aged MSM and must offer early diagnosis and treatment for all MSM.

摘要

目的

我们根据种族/族裔和年龄,研究了男男性行为者(MSM)中的艾滋病毒诊断率和疾病进展情况。

方法

利用从国家艾滋病毒/艾滋病监测系统获得的数据,我们使用泊松回归分析了2001年至2004年艾滋病毒诊断率的趋势。我们采用标准化的Kaplan-Meier方法来确定从艾滋病毒进展到艾滋病的时间差异以及艾滋病生存率。

结果

黑人与西班牙裔男男性行为者的艾滋病毒诊断率高于白人男男性行为者,但2001年至2004年各年龄组内的趋势在种族/族裔方面并无差异。13至19岁(每年14%)、20至24岁(13%)、25至29岁以及40至54岁(3%-6%;各年龄组P≤0.01)的男男性行为者的诊断率有所上升。艾滋病毒诊断后3年未患艾滋病的男男性行为者比例,黑人(66.8%;95%置信区间[CI]=66.1, 67.4)和西班牙裔(68.1%;95% CI=67.5, 68.8)低于白人男男性行为者(74.7%;95% CI=74.2, 75.1)。艾滋病诊断后的3年生存率,黑人低于白人或西班牙裔男男性行为者。

结论

艾滋病毒预防工作应针对年轻和中年男男性行为者,并且必须为所有男男性行为者提供早期诊断和治疗。

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