Corleto Vito D, D'Alonzo Lidia, Zykaj Ermira, Carnuccio Antonella, Chiesara Francesca, Pagnini Cristiano, Di Somma Salvatore, Delle Fave Gianfranco
Department of Digestive and Liver Diseases, II School of Medicine, University La Sapienza, Roma, Italy.
World J Gastroenterol. 2007 Apr 14;13(14):2132-4. doi: 10.3748/wjg.v13.i14.2132.
Oesophageal ulcers occur mainly as a result of gastro-oesophageal reflux disease (GERD). However, pill-induced oesophageal ulcers are a fairly common event. The lesion is mainly due to entrapment of the pill and/or its chemical composition thereof. This case report describes an oesophageal mucosa ulcer occurred in a healthy 35-year old woman who had no previous history of oesophageal disorders and received homeopathic medication. The present case reveals that pill entrapment can occur even in the oesophagus of healthy young individuals and that oesophageal mucosal ulcer can be triggered by substances generally thought devoid of any potentially mucosal aggressive effect.
食管溃疡主要由胃食管反流病(GERD)引起。然而,药物性食管溃疡是相当常见的情况。病变主要是由于药丸滞留和/或其化学成分所致。本病例报告描述了一名35岁健康女性发生的食管黏膜溃疡,该女性既往无食管疾病史,服用了顺势疗法药物。本病例表明,即使在健康年轻个体的食管中也可能发生药丸滞留,并且食管黏膜溃疡可能由通常认为没有任何潜在黏膜侵袭作用的物质引发。