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Etiology, treatment, and outcome of esophageal ulcers: a 10-year experience in an urban emergency hospital.食管溃疡的病因、治疗及转归:一家城市急诊医院的10年经验
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Ann Pharmacother. 2003 Nov;37(11):1675-84. doi: 10.1345/aph.1D056.
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Esophageal ulceration complicating doxycycline therapy.强力霉素治疗引发的食管溃疡
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Drug-induced oesophageal disorders: pathogenesis, incidence, prevention and management.药物性食管疾病:发病机制、发病率、预防及管理
Drug Saf. 2000 Mar;22(3):237-49. doi: 10.2165/00002018-200022030-00007.
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Esophagitis associated with the use of alendronate.与阿仑膦酸盐使用相关的食管炎
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Impaired oesophageal transit of capsule versus tablet formulations in the elderly.老年人中胶囊制剂与片剂制剂的食管转运受损情况。
Gut. 1994 Oct;35(10):1363-7. doi: 10.1136/gut.35.10.1363.
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Effect of dosage form and formulation factors on the adherence of drugs to the esophagus.剂型和制剂因素对药物在食管黏附性的影响。
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一名年轻女性在服用顺势疗法药丸后出现了食管溃疡病例。

A case of oesophageal ulcer developed after taking homeopathic pill in a young woman.

作者信息

Corleto Vito D, D'Alonzo Lidia, Zykaj Ermira, Carnuccio Antonella, Chiesara Francesca, Pagnini Cristiano, Di Somma Salvatore, Delle Fave Gianfranco

机构信息

Department of Digestive and Liver Diseases, II School of Medicine, University La Sapienza, Roma, Italy.

出版信息

World J Gastroenterol. 2007 Apr 14;13(14):2132-4. doi: 10.3748/wjg.v13.i14.2132.

DOI:10.3748/wjg.v13.i14.2132
PMID:17465462
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4319139/
Abstract

Oesophageal ulcers occur mainly as a result of gastro-oesophageal reflux disease (GERD). However, pill-induced oesophageal ulcers are a fairly common event. The lesion is mainly due to entrapment of the pill and/or its chemical composition thereof. This case report describes an oesophageal mucosa ulcer occurred in a healthy 35-year old woman who had no previous history of oesophageal disorders and received homeopathic medication. The present case reveals that pill entrapment can occur even in the oesophagus of healthy young individuals and that oesophageal mucosal ulcer can be triggered by substances generally thought devoid of any potentially mucosal aggressive effect.

摘要

食管溃疡主要由胃食管反流病(GERD)引起。然而,药物性食管溃疡是相当常见的情况。病变主要是由于药丸滞留和/或其化学成分所致。本病例报告描述了一名35岁健康女性发生的食管黏膜溃疡,该女性既往无食管疾病史,服用了顺势疗法药物。本病例表明,即使在健康年轻个体的食管中也可能发生药丸滞留,并且食管黏膜溃疡可能由通常认为没有任何潜在黏膜侵袭作用的物质引发。