Chun Mi-Jin, Shim Eunju, Kho Eun-Hee, Park Keum-Joo, Jung Jarang, Kim Jin-Man, Kim Byunghoon, Lee Ki-Heon, Cho Dong-Lyun, Bai Dong-Hoon, Lee Syng-Ill, Hwang Hyeon-Shik, Ohk Seung-Ho
Department of Oral Microbiology, 2nd Stage of Brain Korea 21 for School of Dentistry, Chonnam National University, Gwangju, South Korea.
Angle Orthod. 2007 May;77(3):483-8. doi: 10.2319/0003-3219(2007)077[0483:SMOOWW]2.0.CO;2.
To test the antiadherent and antibacterial properties of surface modification of orthodontic wires with photocatalytic titanium oxide (TiO(2)).
TiO(2) was coated on the surface of the orthodontic wires by a sol-gel thin film dip-coating method. Bacterial adhesion to the wires was evaluated by the weight change of the wires. The antibacterial activity of the surface-modified orthodontic wires was demonstrated by the dilution agar plate method for Streptococcus mutans and spectrophotometry for Porphyromonas gingivalis.
The orthodontic wires coated with the photocatalytic TiO(2) showed an antiadherent effect against S. mutans compared with the uncoated wires. The bacterial mass that bound to the TiO(2)-coated orthodontic wires remained unchanged, whereas that of the uncoated wires increased by 4.97%. Furthermore, the TiO(2)-coated orthodontic wires had a bactericidal effect on S. mutans and P. gingivalis, which cause dental caries and periodontitis, respectively. The antiadherent and antibacterial mechanisms of TiO(2) to break down the cell wall of those bacteria were revealed by scanning electron microscopy.
The surface modification of orthodontic wires with photocatalytic TiO(2) can be used to prevent the development of dental plaque during orthodontic treatment.
测试光催化二氧化钛（TiO₂）对正畸钢丝表面进行改性后的抗黏附和抗菌性能。
采用溶胶 - 凝胶薄膜浸涂法将TiO₂涂覆在正畸钢丝表面。通过钢丝重量变化评估细菌对钢丝的黏附情况。采用稀释琼脂平板法检测表面改性正畸钢丝对变形链球菌的抗菌活性，采用分光光度法检测对牙龈卟啉单胞菌的抗菌活性。
与未涂覆的钢丝相比，涂覆光催化TiO₂的正畸钢丝对变形链球菌表现出抗黏附作用。与TiO₂涂覆正畸钢丝结合的细菌量保持不变，而未涂覆钢丝的细菌量增加了4.97%。此外，涂覆TiO₂的正畸钢丝对分别导致龋齿和牙周炎的变形链球菌和牙龈卟啉单胞菌具有杀菌作用。通过扫描电子显微镜揭示了TiO₂破坏这些细菌细胞壁的抗黏附和抗菌机制。
用光催化TiO₂对正畸钢丝进行表面改性可用于预防正畸治疗期间牙菌斑的形成。
