Chen Nelson G, Fowlkes J Brian, Carson Paul L, LeCarpentier Gerald L
Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI 48109-0553, USA.
Ultrasound Med Biol. 2007 Jun;33(6):915-23. doi: 10.1016/j.ultrasmedbio.2006.10.017. Epub 2007 Apr 27.
Perfusion imaging in a 3D volume using ultrasound contrast agent may improve vascular characterization compared with 2D imaging. Conventional 3D acquisition requires excessive scan time. A dual transducer technique using conventional systems has been introduced that allows 3D imaging of contrast dynamics with drastically reduced scan times (LeCarpentier et al. 2003). Two transducers are translated across a volume where the leading transducer effects contrast clearance and the following transducer images at desired contrast refill times. With 2D arrays that allow simultaneous clearance and imaging pulses, scan times could be further reduced and the need for two transducers eliminated. The dual transducer technique was demonstrated on a tube phantom, with observed contrast profiles matching those expected. Measured center velocities of (+/- std dev) 1.46 +/- 0.21 and 2.25 +/- 0.5 did not statistically differ from expected values of 1.75 and 2.50 (all mm/s), (p > 0.05). This technique is introduced for rapid acquisition of 3D contrast refill images.
与二维成像相比，使用超声造影剂在三维容积中进行灌注成像可能会改善血管特征描述。传统的三维采集需要过长的扫描时间。已经引入了一种使用传统系统的双换能器技术，该技术能够以大幅缩短的扫描时间对造影剂动力学进行三维成像（勒卡尔庞捷等人，2003年）。两个换能器在一个容积内平移，其中前一个换能器实现造影剂清除，后一个换能器在所需的造影剂再充盈时间进行成像。对于允许同时进行清除和成像脉冲的二维阵列，扫描时间可以进一步缩短，并且不再需要两个换能器。双换能器技术在一个管形体模上得到了验证，观察到的造影剂分布与预期相符。测量得到的中心速度（±标准差）为1.46±0.21和2.25±0.5，与预期值1.75和2.50（均为毫米/秒）在统计学上无差异（p>0.05）。引入该技术是为了快速采集三维造影剂再充盈图像。
