Pawar Rahul S, Shukla Yatin J, Khan Shabana I, Avula Bharathi, Khan Ikhlas A
National Center for Natural Products Research, Research Institute of Pharmaceutical Sciences, University of Mississippi, University, MS 38677, USA.
Steroids. 2007 Jun;72(6-7):524-34. doi: 10.1016/j.steroids.2007.03.003. Epub 2007 Mar 18.
Hoodigosides A-K (1-11), eleven new oxypregnane glycosides and a previously reported oxypregnane glycoside P57AS3 were isolated from the aerial parts of Hoodia gordonii. The structures of these 12-O-beta-tigloyl isoramanone glycosides were determined on the basis of chemical evidence and extensive spectroscopic methods that include one-dimensional and two-dimensional NMR. Cytotoxicity and antioxidant activities of these compounds were tested in cell based assays where they were found to be inactive.
从好望角仙人掌的地上部分分离得到了胡迪糖苷A - K（1 - 11），11种新的氧化孕甾烷糖苷以及一种先前报道过的氧化孕甾烷糖苷P57AS3。这些12 - O - β - 惕各酰异拉马酮糖苷的结构是基于化学证据以及包括一维和二维核磁共振在内的广泛光谱方法确定的。在基于细胞的实验中测试了这些化合物的细胞毒性和抗氧化活性，结果发现它们没有活性。
