Coimbra Carlos E A, Basta Paulo C
Escola Nacional de Saúde Pública, Fundação Oswaldo Cruz, Rua Leopoldo Bulhões 1480, Rio de Janeiro, RJ 21041-210, Brazil.
Trans R Soc Trop Med Hyg. 2007 Jul;101(7):635-6. doi: 10.1016/j.trstmh.2007.03.013. Epub 2007 Apr 30.
Tuberculosis (TB) stands out as one of the principal infectious diseases affecting Amazonian Indians. Recent research indicates that incidence rates among indigenous peoples may be as much as ten times higher than those of the general Brazilian population. Purified protein derivative reactivity in Amazonia is low compared with populations of European descent; anergy rates usually surpass 50%, even under high BCG coverage. An annual risk of infection of 1.2-2.2% points to high rates of transmission. Whether or not particular susceptibility to TB is linked to genetics, Amazonian Indians face a disproportionately high risk of contracting and dying from TB.
结核病是影响亚马孙印第安人的主要传染病之一。最近的研究表明，原住民中的发病率可能比巴西普通人群高出多达十倍。与欧洲裔人群相比，亚马孙地区的纯化蛋白衍生物反应性较低；即使在卡介苗高接种率的情况下，无反应率通常也超过50%。每年1.2%-2.2%的感染风险表明传播率很高。无论对结核病的特殊易感性是否与基因有关，亚马孙印第安人感染结核病并死于该病的风险都高得不成比例。
