Chen Yong, Han Kun-Ying, Liu Yu
Department of Chemistry, State Key Laboratory of Elemento-Organic Chemistry, Nankai University, Tianjin 300071, PR China.
Bioorg Med Chem. 2007 Jul 1;15(13):4537-42. doi: 10.1016/j.bmc.2007.04.016. Epub 2007 Apr 10.
A water-soluble 8-aminoquinolino-beta-cyclodextrin/1-adamantaneacetic acid (1/ADA) system is prepared in situ and exhibits a unique switch-on fluorescence response to Zn(2+) over other common metal ions. Spectrophotometric studies demonstrate that this system can strongly coordinate Zn(2+) through a cyclodextrin/substrate/metal triple recognition mode, and the resulting 1/ADA/Zn(2+) ternary complex emits the blue-green fluorescence (lambda=490nm) that can be easily distinguished by eyes in aqueous solution. Significantly, the switch-on fluorescence response of 1/ADA to Zn(2+) is barely affected by various metal ions except Cu(2+). As a result, this system can behave as an efficient supramolecular fluorescence sensor for Zn(2+) in water.
一种水溶性8-氨基喹啉-β-环糊精/1-金刚烷乙酸（1/ADA）体系原位制备而成，相较于其他常见金属离子，它对Zn(2+)呈现出独特的荧光开启响应。分光光度研究表明，该体系可通过环糊精/底物/金属三元识别模式与Zn(2+)强烈配位，生成的1/ADA/Zn(2+)三元络合物在水溶液中发射出蓝绿色荧光（λ=490nm），肉眼可轻松辨别。值得注意的是，1/ADA对Zn(2+)的荧光开启响应除了受Cu(2+)影响外，几乎不受其他各种金属离子的影响。因此，该体系可作为水中Zn(2+)的高效超分子荧光传感器。
