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[家猪中涉及6号染色体的两种新型相互易位]

[Two novel reciprocal translocations involving chromosome 6 in the domestic pig].

作者信息

Bonneau M, Boscher J, Delate J J, Legault C, Popescu C P

机构信息

INRA, CRJ Installations Expérimentales Porcines de la Minière, Jouy-en-Josas, France.

出版信息

Ann Genet. 1991;34(2):65-9.

PMID:1746885
Abstract

In the present study 2 new reciprocal translocations are described in two hypoprolific boars. The first one, a Gascon/Meishan boar, has produced a mean value of 7.37 +/- 0.69 piglets, vs 12.41 +/- 0.22 piglets per litter in contemporaries. The second one, a Pietrain/Large-White boar, has produced a mean of 5.42 +/- 0.69 vs 12.41 +/- 0.22 piglets per litter in contemporaries. Each of these animals carries a new chromosome translocation involving chromosomes 6, 8 and 15, respectively. The first translocation seems to be a de novo occurring abnormality. The economic consequences of these abnormalities are discussed. Carrier of the gene HAL, the abnormal chromosomes 6 involved in these translocations are important, and could useful markers in gene mapping and flow cytometry studies in pigs.

摘要

在本研究中,描述了两头低产公猪的两种新的相互易位情况。第一头是加斯科尼/梅山公猪,其每窝产仔的平均值为7.37±0.69头仔猪,而同期的仔猪每窝平均产仔数为12.41±0.22头。第二头是皮特兰/大白公猪,其每窝平均产仔5.42±0.69头,而同期每窝平均产仔12.41±0.22头。这两头猪分别携带一种涉及6号、8号和15号染色体的新的染色体易位。第一种易位似乎是一种新生的异常情况。讨论了这些异常情况的经济后果。这些易位中涉及的异常6号染色体携带HAL基因,它们很重要,可能是猪基因图谱绘制和流式细胞术研究中的有用标记。

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