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[胰腺。先天性改变、急性和慢性胰腺炎]

[Pancreas. Congenital changes, acute and chronic pancreatitis].

作者信息

Schima W, Ba-Ssalamah A, Plank C, Kulinna-Cosentini C, Püspök A

机构信息

Universitätsklinik für Radiodiagnostik, Medizinische Universität Wien, Wien, Osterreich. wolf

出版信息

Radiologe. 2007 May;47 Suppl 1:S41-55; quiz S56. doi: 10.1007/s00117-007-1497-5.

Abstract

The pancreas develops from ventral and dorsal buds, which undergo fusion. Failure to fuse results in pancreas divisum, which is defined by separate pancreatic ductal systems draining into the duodenum. Risk of developing pancreatitis is increased in pancreas divisum. MR cholangiopancreatography (MRCP) is the technique of choice for detecting it non-invasively. Annular pancreas is the result of incomplete rotation of the pancreatic bud around the duodenum with the persistence of parenchyma or a fibrous band encircling (stenosing) the duodenum. Acute pancreatitis is usually caused by bile duct stones or alcohol abuse. Contrast-enhanced multi-detector row CT is the method of choice to assess the extent of this disease. In acute pancreatitis, the role of MRCP is mainly limited to finding bile duct stones in patients with suspected biliary pancreatitis. Chronic pancreatitis results in relentless and irreversible loss of exocrine (and sometimes endocrine) function of the pancreas. MDCT even shows subtle calcifications. MRCP is the method of choice for non-invasive assessment of the duct. Inflammatory pseudotumor in chronic pancreatitis and groove pancreatitis are difficult to differentiate from pancreatic cancer. In these cases, multiple imaging methods such as MDCT, MRI and endosonography including biopsy may be used to make a diagnosis.

摘要

胰腺由腹侧和背侧芽发育而来,二者会发生融合。未能融合则会导致胰腺分裂,其定义为分别有胰管系统引流至十二指肠。胰腺分裂会增加患胰腺炎的风险。磁共振胰胆管造影(MRCP)是无创检测胰腺分裂的首选技术。环状胰腺是胰芽围绕十二指肠旋转不完全,致使实质组织持续存在或有纤维带环绕(狭窄)十二指肠的结果。急性胰腺炎通常由胆管结石或酗酒引起。对比增强多层螺旋CT是评估该病范围的首选方法。在急性胰腺炎中,MRCP的作用主要局限于在疑似胆源性胰腺炎患者中发现胆管结石。慢性胰腺炎会导致胰腺外分泌(有时也包括内分泌)功能持续且不可逆的丧失。多层螺旋CT甚至能显示细微的钙化。MRCP是无创评估胰管的首选方法。慢性胰腺炎中的炎性假瘤和沟部胰腺炎很难与胰腺癌区分开来。在这些病例中,可能会使用多种成像方法,如多层螺旋CT、MRI和包括活检在内的内镜超声检查来进行诊断。

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