Tenorio López Fermín Alejandro, del Valle Mondragón Leonardo, Pastelín Hernández Gustavo
Departamento de Farmacología, Instituto Nacional de Cardiología "Ignacio Chavez", México, D.F.
Arch Cardiol Mex. 2006 Oct-Dec;76 Suppl 4:S33-45.
It has been suggested that dietary intake of flavonoids may reduce the risk of cardiovascular diseases. On the other hand, in vitro and in vivo studies shows that flavonoids has a vast array of biological activities. Our aim in this review is to put in evidence the effect of flavonoids on several enzymatic systems that could act as potential therapeutic targets, based on the reports of diverse research groups, leaders in the natural products research area, have published through the years, and with the goal of consolidating those results with the findings provided by some epidemiological studies, could support the introduction of these compounds into the clinic.
有人认为，饮食中摄入类黄酮可能会降低心血管疾病的风险。另一方面，体外和体内研究表明，类黄酮具有广泛的生物活性。在这篇综述中，我们的目的是根据天然产物研究领域的多个领先研究小组多年来发表的报告，证明类黄酮对几种可能作为潜在治疗靶点的酶系统的作用，并将这些结果与一些流行病学研究的结果相结合，以期支持将这些化合物引入临床。
