Kosior Piotr, Kaczmarek Urszula
Zaklad Propedeutyki Stomatologicznej Akademii Medycznej we Wrocławiu
Ann Acad Med Stetin. 2006;52 Suppl 1:61-5.
Low fluoride concentrations constantly maintained in the oral cavity are important for caries prevention. Application of fissure sealants containing fluoride improves protection and reinforces caries prophylaxis. The aim of this study was to assess the level of fluoride release from Conseal F fissure sealant in different media.
Sealant samples were placed in (a) artificial saliva without calcium ions (C++) at pH of 4.5, 5.5, 6.0, 7.0, and 7.5, (b) artificial saliva with calcium ions (Ca") at pH 4.5, and 5.5, (c) saline, and (d) deionized water. Fluoride concentration in solution was measured after 1, 3, 24, 48, 72, and 168 hours from the start of the experiment.
The highest cumulative fluoride concentration was found in saline (9.39 +/- 2.17 microg F/mm(2)), the lowest in artificial saliva at pH of 7.0 (0.45+/-0.14 microg F/mm(2)). The highest fluoride emission was observed during the first three hours which then decreased to a low but relatively stable level.
The level of fluoride release from Conseal F fissure sealant depends on composition and pH of the medium. Decrease in pH increased fluoride release. This property is essential for patients with low salivary pH and high risk of caries.
口腔中持续保持低氟浓度对预防龋齿很重要。应用含氟的窝沟封闭剂可提高保护效果并加强龋齿预防。本研究的目的是评估Conseal F窝沟封闭剂在不同介质中的氟释放水平。
将封闭剂样品置于（a）pH值为4.5、5.5、6.0、7.0和7.5的无钙离子（C++）人工唾液中，（b）pH值为4.5和5.5的含钙离子（Ca）人工唾液中，（c）盐水中，以及（d）去离子水中。从实验开始后1、3、24、48、72和168小时测量溶液中的氟浓度。
在盐水中发现最高的累积氟浓度（9.39±2.17μg F/mm²），在pH值为7.0的人工唾液中最低（0.45±0.14μg F/mm²）。在最初三小时观察到最高的氟释放量，随后降至低但相对稳定的水平。
Conseal F窝沟封闭剂的氟释放水平取决于介质的成分和pH值。pH值降低会增加氟释放。这一特性对唾液pH值低且患龋风险高的患者至关重要。
