Soliman Manal M, Bishara Samir E, Wefel James, Heilman Judi, Warren John J
Department of Conservative Dentistry, College of Dentistry, Al-Menia University, Egypt.
Angle Orthod. 2006 Mar;76(2):282-8. doi: 10.1043/0003-3219(2006)076[0282:FRRFAO]2.0.CO;2.
The objectives were to measure the rate and amount of fluoride ions released from the sealant over a period of 17 weeks and to determine whether the fluoride-releasing sealant has a recharging ability when fluoride ions are reintroduced into the environment. Disc-shaped specimens were prepared from two types of sealants: (1) 10 discs were made using a fluoride-releasing sealant and (2) 10 discs were made of a nonfluoride adhesive primer (control). An ion analyzer was used to measure the fluoride release using a fluoride ion-specific combination electrode. The results of the repeated measure analysis (F = 7.76) indicated that the fluoride-containing sealant released fluoride ions into the solution in sustained but significantly (P = .014) decreasing rates from a high of 0.074 +/- 0.04 ppm/week/mm2 in the first week to a low of 0.015 +/- 0.017 ppm/week/mm2 at the end of the 17th week. Furthermore, the Pro Seal discs had the ability to be recharged with fluoride ions introduced from a foaming solution of acidulated phosphate fluoride. The mean fluoride release rate one week after recharging was 0.354 +/- 0.095 ppm/week/mm2 and decreased to 0.014 +/- 0.009 ppm/week/mm2 after eight weeks. The control sealant showed no significant fluoride release and was unable to absorb the fluoride ions available in the solution. The fluoride-containing sealant Pro Seal released fluoride ions in sustained but significantly decreasing amounts. The Pro Seal discs had the ability to be recharged with fluoride ions.
目的是测量密封剂在17周内释放氟离子的速率和量，并确定当氟离子重新引入环境时，含氟释放密封剂是否具有再充电能力。从两种类型的密封剂制备圆盘形试样：（1）使用含氟释放密封剂制作10个圆盘，（2）使用非氟粘合剂底漆制作10个圆盘（对照）。使用离子分析仪通过氟离子特异性组合电极测量氟释放量。重复测量分析结果（F = 7.76）表明，含氟密封剂以持续但显著（P = 0.014）下降的速率将氟离子释放到溶液中，从第一周的0.074±0.04 ppm/周/平方毫米的高位降至第17周结束时的0.015±0.017 ppm/周/平方毫米的低位。此外，Pro Seal圆盘能够从酸化磷酸氟的发泡溶液中引入的氟离子进行再充电。再充电一周后的平均氟释放速率为0.354±0.095 ppm/周/平方毫米，八周后降至0.014±0.009 ppm/周/平方毫米。对照密封剂未显示出显著的氟释放，并且无法吸收溶液中可用的氟离子。含氟密封剂Pro Seal以持续但显著减少的量释放氟离子。Pro Seal圆盘具有用氟离子再充电的能力。
