Vojniković Bozidar, Vojniković Davor, Brcić Luka
Eye Polyclinic 'Dr. B. Vojniković", Rijeka, Croatia.
Coll Antropol. 2007 Jan;31 Suppl 1:29-31.
In 14 experimental Cavia Coba'ya eyes were irradiated with UV-B light, lambda 312 nm, 25 J/cm2 in 15 minute exposure. Including the transmission of light through optical media: cornea, lens, humor aqueous and vitreous body, and pupil surface of 7 mm2, we can calculate that in these conditions retina can be really irradiated with 10 J/cm2. The half number of Cavia Coba'ya was simultaneously irradiated with visible light, lambda of 550-600 nm (1000 Lx). Control group was 5 Cavia Coba'ya. Two months after irradiation, eyes were enucleated and fixed in 4% formaldehyde. Histopathological findings showed alterations of all retinal layers: loss of ganglion cells, axons, reduction of photoreceptors, vacuolar degeneration and hyperplasia of retinal pigment epithelium. In the second group of irradiance, the eyes with visible light lambda 550-600 nm, all retinal alterations were in 50% decreased.
对14只实验用天竺鼠的眼睛用波长312nm的UV - B光进行照射，剂量为25J/cm²，照射时间15分钟。考虑到光线透过角膜、晶状体、房水和玻璃体等光学介质以及7mm²的瞳孔表面的情况，我们可以计算出在这些条件下视网膜实际接受的照射剂量为10J/cm²。同时，半数天竺鼠还用波长550 - 600nm（1000勒克斯）的可见光进行照射。对照组为5只天竺鼠。照射两个月后，摘除眼球并固定于4%的甲醛溶液中。组织病理学检查结果显示视网膜各层均有改变：神经节细胞和轴突缺失、光感受器减少、视网膜色素上皮细胞空泡样变性和增生。在第二组光照实验中，用波长550 - 600nm可见光照射的眼睛，所有视网膜改变减少了50%。
