Shah Kara N, Honig Paul J, Yan Albert C
Section of Pediatric Dermatology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, USA.
Pediatrics. 2007 May;119(5):e1177-83. doi: 10.1542/peds.2006-1553.
Acute annular urticaria is a common and benign cutaneous hypersensitivity reaction seen in children that manifests with characteristic annular, arcuate, and polycyclic urticarial lesions in association with acral edema. It is mistaken most often for erythema multiforme and, occasionally, for a serum-sickness-like reaction. Although these 3 entities may present in a similar manner, specific clinical features help to distinguish them, and it is important for the clinician to be able to differentiate among them. We present herein a series of 18 patients who were given a diagnosis of acute annular urticaria and review the clinical distinctions between acute annular urticaria, serum-sickness-like reactions, and erythema multiforme. Because of the frequency of its clinical confusion with erythema multiforme, we propose the term "urticaria multiforme" as a more apt description to highlight the distinctive clinical features of this urticaria variant.
急性环状荨麻疹是儿童常见的良性皮肤过敏反应，表现为特征性的环状、弓形和多环状荨麻疹皮损，并伴有肢端水肿。它最常被误诊为多形红斑，偶尔也会被误诊为血清病样反应。尽管这三种疾病可能以相似的方式呈现，但特定的临床特征有助于区分它们，临床医生能够对它们进行鉴别很重要。我们在此报告了一系列18例被诊断为急性环状荨麻疹的患者，并回顾了急性环状荨麻疹、血清病样反应和多形红斑之间的临床区别。由于其临床上常与多形红斑混淆，我们提出“多形性荨麻疹”这一术语作为更恰当的描述，以突出这种荨麻疹变体的独特临床特征。
