Cohen Arazi Laura, Suárez Patricia G, Villa Nova Susana, Laporta Victoria, Díaz Sandoval Daniel A, Rojas Jaramillo Kathya A
Department of Pediatrics, Hospital General de Agudos Dr. J. A. Fernández, City of Buenos Aires, Argentina.
Arch Argent Pediatr. 2025 Apr 1;123(2):e202410442. doi: 10.5546/aap.2024-10442.eng. Epub 2024 Sep 12.
Urticaria multiforme is an allergic hypersensitivity reaction. It manifests as a skin reaction with a vascular response pattern in the dermis. Urticaria multiforme is a benign, self-limited condition of unknown etiology, with onset in pediatric age and a more frequent range of presentation in children from 4 months to 4 years old. It is considered a subtype of urticaria in which the skin lesion corresponds to particular annular and polycyclic wheals, with a purple center and evanescent nature, frequently associated with acral edema and fever. The clinical recognition of urticaria multiforme, together with an adequate symptomatology, are sufficient for the diagnosis and provide peace of mind to parents. The most important differential diagnoses include acute urticaria, urticarial vasculitis, and erythema multiforme. The objectives of this article are to train pediatricians in recognizing urticaria multiforme and the differential diagnoses and to highlight the importance of symptomatology in reaching a diagnosis.
多形性荨麻疹是一种过敏性超敏反应。它表现为一种皮肤反应，在真皮层呈现血管反应模式。多形性荨麻疹是一种病因不明的良性、自限性疾病，发病于儿童期，在4个月至4岁的儿童中更为常见。它被认为是荨麻疹的一种亚型，其皮肤损害对应于特定的环形和多环形风团，中心呈紫色且具有短暂性，常伴有肢端水肿和发热。多形性荨麻疹的临床识别以及充分的症状表现足以进行诊断，并让家长安心。最重要的鉴别诊断包括急性荨麻疹、荨麻疹性血管炎和多形红斑。本文的目的是培训儿科医生识别多形性荨麻疹及其鉴别诊断，并强调症状表现对做出诊断的重要性。
