Rulli Nestor E, Melton Julian, Wilmes Anja, Ewart Gary, Mahalingam Suresh
Centre for Virus Research, School of Health Sciences, University of Canberra, Canberra, ACT, Australia.
Ann N Y Acad Sci. 2007 Apr;1102:96-108. doi: 10.1196/annals.1408.007.
Alphaviruses such as the Sindbis-group viruses, Scandinavian Ockelbo virus, the African Asian chikungunya virus, the African O'nyong-nyong virus, the South American Mayaro virus, and the Australasian Barmah Forest and Ross River viruses, are commonly associated with outbreaks of acute and persistent arthritis and arthralgia in humans. The mechanisms by which these viruses cause arthritis/arthralgia are poorly understood. This chapter summarizes our current understanding of viral arthritides using our newly developed mouse model of Ross River virus-induced joint and muscle inflammation.
诸如辛德毕斯病毒属病毒、斯堪的纳维亚奥克尔博病毒、亚非基孔肯雅病毒、非洲奥尼昂尼昂病毒、南美马亚罗病毒以及澳大拉西亚巴马森林病毒和罗斯河病毒等甲病毒，通常与人类急性和持续性关节炎及关节痛的暴发有关。这些病毒引发关节炎/关节痛的机制尚不清楚。本章利用我们新开发的罗斯河病毒诱导的关节和肌肉炎症小鼠模型，总结了我们目前对病毒性关节炎的认识。
