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感染所致腹膜透析相关性真菌性腹膜炎的诊断与治疗

Diagnosis and treatment of peritoneal dialysis associated mycotic peritonitis caused by infection.

作者信息

Zhang Dan, Mao Guofeng, Liang Meichun, Sun Guiqin, Yu Debao

机构信息

Department of Clinical Laboratory Center, Shaoxing People's Hospital, Shaoxing, 312000, PR China.

School of Medical Technology and Information Engineering, Zhejiang Chinese Medical University, Hangzhou, 310053, PR China.

出版信息

Med Mycol Case Rep. 2024 May 1;44:100651. doi: 10.1016/j.mmcr.2024.100651. eCollection 2024 Jun.

Abstract

peritonitis is a rare but highly severe complication of peritoneal dialysis with a high mortality rate. We report a case of peritonitis. Despite early removal of the catheter and oral voriconazole antifungal treatment for 3 weeks, the treatment effect was unsatisfactory, resulting in prolonged hospital stay and affecting the patient's quality of life. After switching to liposomalAmphotericin B, inflammation indicators rapidly decreased and infection was controlled. Liposomalamphotericin B provides an option for treatment of peritonitis.

摘要

腹膜炎是腹膜透析罕见但极为严重的并发症,死亡率很高。我们报告一例腹膜炎病例。尽管早期拔除导管并口服伏立康唑进行抗真菌治疗3周,但治疗效果不理想,导致住院时间延长并影响患者生活质量。改用两性霉素B脂质体后,炎症指标迅速下降,感染得到控制。两性霉素B脂质体为腹膜炎治疗提供了一种选择。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f5a/11087944/8529531afc55/gr1.jpg

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