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感染所致腹膜透析相关性真菌性腹膜炎的诊断与治疗

Diagnosis and treatment of peritoneal dialysis associated mycotic peritonitis caused by infection.

作者信息

Zhang Dan, Mao Guofeng, Liang Meichun, Sun Guiqin, Yu Debao

机构信息

Department of Clinical Laboratory Center, Shaoxing People's Hospital, Shaoxing, 312000, PR China.

School of Medical Technology and Information Engineering, Zhejiang Chinese Medical University, Hangzhou, 310053, PR China.

出版信息

Med Mycol Case Rep. 2024 May 1;44:100651. doi: 10.1016/j.mmcr.2024.100651. eCollection 2024 Jun.

DOI:10.1016/j.mmcr.2024.100651
PMID:38737129
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11087944/
Abstract

peritonitis is a rare but highly severe complication of peritoneal dialysis with a high mortality rate. We report a case of peritonitis. Despite early removal of the catheter and oral voriconazole antifungal treatment for 3 weeks, the treatment effect was unsatisfactory, resulting in prolonged hospital stay and affecting the patient's quality of life. After switching to liposomalAmphotericin B, inflammation indicators rapidly decreased and infection was controlled. Liposomalamphotericin B provides an option for treatment of peritonitis.

摘要

腹膜炎是腹膜透析罕见但极为严重的并发症，死亡率很高。我们报告一例腹膜炎病例。尽管早期拔除导管并口服伏立康唑进行抗真菌治疗3周，但治疗效果不理想，导致住院时间延长并影响患者生活质量。改用两性霉素B脂质体后，炎症指标迅速下降，感染得到控制。两性霉素B脂质体为腹膜炎治疗提供了一种选择。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f5a/11087944/88dcdad1faa7/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f5a/11087944/8529531afc55/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f5a/11087944/e7fa78924d60/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f5a/11087944/88dcdad1faa7/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f5a/11087944/8529531afc55/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f5a/11087944/e7fa78924d60/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f5a/11087944/88dcdad1faa7/gr3.jpg

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本文引用的文献

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Peritonitis due to in peritoneal dialysis patients.腹膜透析患者因[未提及具体病因]导致的腹膜炎 。 （你提供的原文中“due to”后面缺少具体内容）
Med Mycol Case Rep. 2023 Mar 22;40:44-46. doi: 10.1016/j.mmcr.2023.03.005. eCollection 2023 Jun.
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Liposomal amphotericin B-the past.脂质体两性霉素 B-过去。
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Amphotericin B: A drug of choice for Visceral Leishmaniasis.两性霉素B：内脏利什曼病的首选药物。
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Aspergillus peritonitis in peritoneal dialysis patients: A systematic review.腹膜透析患者中的曲霉菌腹膜炎：一项系统性综述。
J Mycol Med. 2020 Dec;30(4):101037. doi: 10.1016/j.mycmed.2020.101037. Epub 2020 Aug 20.
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(1→3)-β-D-glucan and galactomannan testing for the diagnosis of fungal peritonitis in peritoneal dialysis patients, a pilot study.(1→3)-β-D-葡聚糖和半乳甘露聚糖检测用于诊断腹膜透析患者真菌性腹膜炎的初步研究
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Aspergillus Niger peritonitis in a peritoneal dialysis patient treated with eculizumab.黑曲霉腹膜炎在接受依库珠单抗治疗的腹膜透析患者中的应用。
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