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腹膜透析中的曲霉性腹膜炎:病例报告及文献综述

Aspergillus peritonitis in peritoneal dialysis: case report and a review of the literature.

作者信息

Tanis B C, Verburgh C A, van 't Wout J W, van der Pijl J W

机构信息

Department of Nephrology, University Hospital Leiden, The Netherlands.

出版信息

Nephrol Dial Transplant. 1995;10(7):1240-3.

PMID:7478133
Abstract

Aspergillus peritonitis is a rare complication of continuous ambulatory peritoneal dialysis. The case is described of a 68-year-old man in whom Aspergillus fumigatus was isolated from the peritoneal dialysate after recurrent peritonitis with Gram-negative rods in association with diverticulosis. Treatment consisting of removal of the catheter and intravenous administration of amphotericin B followed by oral itraconazole was successful. A review of the sparse literature (12 cases) displays uncertainties regarding diagnostic awareness, culture diagnosis, and therapeutic management. Next to institution of appropriate antifungal therapy, early removal of the peritoneal dialysis catheter is recommended, as delayed removal of the catheter appears to be associated with increased mortality and morbidity.

摘要

曲霉性腹膜炎是持续性非卧床腹膜透析的一种罕见并发症。本文描述了一例68岁男性患者,该患者在复发性腹膜炎伴革兰氏阴性杆菌及憩室病后,从腹膜透析液中分离出烟曲霉。治疗方法包括拔除导管及静脉注射两性霉素B,随后口服伊曲康唑,治疗成功。对少量文献(12例)的回顾显示,在诊断意识、培养诊断及治疗管理方面存在不确定性。除了采取适当的抗真菌治疗外,建议尽早拔除腹膜透析导管,因为延迟拔除导管似乎与死亡率和发病率增加有关。

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