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比利时普通人群精神障碍的终生风险和发病年龄。

Lifetime risk and age-of-onset of mental disorders in the Belgian general population.

作者信息

Bonnewyn Anke, Bruffaerts Ronny, Vilagut Gemma, Almansa Josué, Demyttenaere Koen

机构信息

Dept. of Neurosciences and Psychiatry, University Hospital Gasthuisberg, Leuven, Belgium.

出版信息

Soc Psychiatry Psychiatr Epidemiol. 2007 Jul;42(7):522-9. doi: 10.1007/s00127-007-0191-2. Epub 2007 Apr 30.

DOI:10.1007/s00127-007-0191-2
PMID:17473902
Abstract

AIMS

To estimate lifetime risk and age of onset of mental disorders in the adult general population of Belgium.

METHOD AND MATERIALS

For the World Mental Health Surveys of the World Health Organization, a representative random sample of non-institutionalized inhabitants from Belgium aged 18 or older (n = 2419) were interviewed between April 2001 and June 2002. The interview took place by means of the Composite International Diagnostic Interview, version 3.0. Lifetime prevalence, projected lifetime risk, and age-of-onset of mental disorders were assessed.

RESULTS

Lifetime risk for any mental disorder was 37.1%: 22.8% for mood disorders, 15.7% for anxiety disorders, and 10.8% for alcohol disorders. Median age of onset was 38 years for mood, 14 years for anxiety, and 23 years for alcohol disorders. Prevalence estimates of mood and alcohol disorders were significantly higher in the cohorts between 18 and 34 years.

CONCLUSION

This is the first study that assessed projected lifetime risk and age of onset of mental disorders in the Belgian general population. About one-third of the Belgian non-institutionalized adult population will meet the criteria for a DSM-IV mental disorder at some time during their life. Median age of onset varies from disorder to disorder and younger cohorts had higher likelihood for developing mental disorders.

摘要

目的

评估比利时成年普通人群中精神障碍的终生风险和发病年龄。

方法与材料

针对世界卫生组织的世界心理健康调查,于2001年4月至2002年6月期间,对比利时18岁及以上非机构化居民的代表性随机样本(n = 2419)进行了访谈。访谈通过综合国际诊断访谈第3.0版进行。评估了精神障碍的终生患病率、预计终生风险和发病年龄。

结果

任何精神障碍的终生风险为37.1%:情绪障碍为22.8%,焦虑障碍为15.7%,酒精障碍为10.8%。情绪障碍的发病年龄中位数为38岁,焦虑障碍为14岁,酒精障碍为23岁。18至34岁人群中情绪障碍和酒精障碍的患病率估计值显著更高。

结论

这是第一项评估比利时普通人群中精神障碍预计终生风险和发病年龄的研究。约三分之一的比利时非机构化成年人口在其一生中的某个时候将符合DSM-IV精神障碍的标准。发病年龄中位数因障碍类型而异,较年轻人群患精神障碍的可能性更高。

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