Wilkinson Anna V, Schabath Matthew B, Prokhorov Alexander V, Spitz Margaret R
Department of Epidemiology, The University of Texas M. D. Anderson Cancer Center, P.O. Box 301439, Houston, TX 77230, USA.
Cancer Causes Control. 2007 Aug;18(6):635-44. doi: 10.1007/s10552-007-9008-6. Epub 2007 May 1.
We sought to determine whether the influence of two factors known to influence smoking initiation (parental smoking and lower academic attainment) vary by age of smoking initiation and to develop profiles of smokers based on their age of smoking initiation. We analyzed data on demographic and smoking characteristics from 1,447 former and current cancer-free smokers, born between 1912 and 1975, who served as controls in an ongoing lung cancer case-control study, and who reported initiating smoking before their 31st birthday. Parental smoking exerted a significant influence among the youngest initiators (<15 years) only, and the magnitude of the influence from academic attainment decreased with increasing age of initiation. The youngest initiators were less likely to have quit, had smoked for more years, and reported higher levels of nicotine dependence than the oldest initiators. Our results underscore the continued need to target smoking prevention messages toward individuals younger than 15 years. Because the influence of parental smoking was pronounced among the youngest initiators, family smoking dynamics must be addressed to develop effective prevention programs tailored to this at-risk age group.
我们试图确定已知影响开始吸烟的两个因素（父母吸烟和学业成绩较低）的影响是否因开始吸烟的年龄而异，并根据开始吸烟的年龄制定吸烟者概况。我们分析了1447名曾吸烟和目前仍在吸烟的无癌吸烟者的人口统计学和吸烟特征数据，这些人出生于1912年至1975年之间，在一项正在进行的肺癌病例对照研究中作为对照，且报告在31岁之前开始吸烟。父母吸烟仅对最年轻的开始吸烟者（<15岁）有显著影响，学业成绩的影响程度随着开始吸烟年龄的增加而降低。最年轻的开始吸烟者比最年长的开始吸烟者戒烟的可能性更小，吸烟年限更长，且尼古丁依赖水平更高。我们的结果强调了持续需要针对15岁以下个体开展吸烟预防信息宣传。由于父母吸烟的影响在最年轻的开始吸烟者中较为明显，因此必须解决家庭吸烟动态问题，以制定针对这一高危年龄组的有效预防方案。
