Park Sang Min, Son Ki Young, Lee Young Joon, Lee Hee-Choon S, Kang Ji Ho, Lee Yeon Ji, Chang Yoon Jung, Yun Young Ho
Quality of Cancer Care Branch, Research Institute and Hospital, National Cancer Center 809, Madu-dong, Ilsan-gu, Goyang-si, Gyeonggi-do 411-769, South Korea.
Drug Alcohol Depend. 2004 May 10;74(2):197-203. doi: 10.1016/j.drugalcdep.2004.01.001.
Few studies have investigated the association between age at smoking initiation and Fagerström test for nicotine dependence (FTND) in adulthood. The goal of this study was to develop the Korean version of FTND (FTND-K) and to examine the relationship between age at smoking initiation and nicotine dependence.
This investigation used data from 268 current smokers who visited the Center for Cancer Prevention and Early Detection in the National Cancer Center, Korea. The internal consistency of the FTND-K was assessed by Cronbach's coefficient alpha. Pearson's correlation coefficients were used to assess the relationships between the FTND-K sum scores and urinary cotinine levels. One-way analysis of variance (ANOVA) and t-tests were used to assess differences in the FTND-K sum score between groups. Factor associated with nicotine dependence were identified through stepwise multiple logistic regression analysis.
The standardized Cronbach's alpha of FTND-K was 0.72. A significant positive correlation was seen between the FTND-K sum score and urinary cotinine level (correlation coefficient = 0.49, P < 0.05). Age at smoking initiation had a significant association with the FTND-K sum score in univariate analysis. In multivariate analysis, nicotine dependence was higher in smokers that started smoking cigarettes at 19 years or earlier than in those that started at 25 years or later (OR = 11.25, 95% CIs, 1.46-97.10).
The FTND-K is a valid assessment tool of nicotine dependence with acceptable levels of internal consistency and close correlation to urinary cotinine level. The finding that those who initiate smoking at an early age tend to be more nicotine dependent underscores and reinforces the public health significance of delaying smoking onset.
很少有研究调查成年期开始吸烟的年龄与尼古丁依赖的法格斯特龙测试（FTND）之间的关联。本研究的目的是开发FTND的韩语版本（FTND-K），并研究开始吸烟的年龄与尼古丁依赖之间的关系。
本调查使用了来自韩国国立癌症中心癌症预防与早期检测中心的268名当前吸烟者的数据。通过克朗巴赫系数α评估FTND-K的内部一致性。使用皮尔逊相关系数评估FTND-K总分与尿可替宁水平之间的关系。采用单因素方差分析（ANOVA）和t检验评估各组之间FTND-K总分的差异。通过逐步多元逻辑回归分析确定与尼古丁依赖相关的因素。
FTND-K的标准化克朗巴赫α为0.72。FTND-K总分与尿可替宁水平之间存在显著正相关（相关系数 = 0.49，P < 0.05）。在单因素分析中，开始吸烟的年龄与FTND-K总分有显著关联。在多因素分析中，19岁或更早开始吸烟的吸烟者的尼古丁依赖程度高于25岁或更晚开始吸烟的吸烟者（OR = 11.25，95%置信区间，1.46 - 97.10）。
FTND-K是一种有效的尼古丁依赖评估工具，具有可接受的内部一致性水平，且与尿可替宁水平密切相关。早年开始吸烟的人往往尼古丁依赖程度更高这一发现强调并强化了推迟吸烟开始时间的公共卫生意义。
