Ierardi E, Monno R, Mongelli A, Allegretta L, Milone E, Rizzi S, Panza P, Coppolecchia P, Francavilla A
Cattedra di Malattie dell'Apparato Digerente ed Endoscopia Digestiva, Università degli Studi di Bari, Italy.
Ital J Gastroenterol. 1991 Feb;23(2):86-7.
Recently a spiral bacterium different from Helicobacter Pylori (HP) was observed in the human stomach and the name of Gastrospirillum Hominis (GH) was proposed for this organism. GH presence is reported to be not associated to HP but related to chronic active gastritis. We describe the case of a 31 year old male suffering from upper abdominal symptoms, who underwent oesophagogastroduodenoscopy, which revealed a picture of duodenal hyperemia. Gastric body showed a normal mucosa and absence of HP, while active chronic gastritis associated with HP was found in the antrum. In addition few spiral bacteria showing 4-5 spirals, larger than HP were observed within the gastric crypts and beneath the mucus layer in this site. This case represents the first report from our geographic area (Southern Italy) of the possibility of finding bacteria different from HP in the human stomach. The simultaneous HP presence does not allow us to relate the chronic active gastritis of the patient with the GH like bacteria. Our finding, however, suggests the possibility that HP and GH may be simultaneously present in the course of type B antral chronic inflammation. This association was not observed in previous investigations.
最近，在人的胃中观察到一种不同于幽门螺杆菌（HP）的螺旋菌，并为此微生物提出了人胃螺旋菌（GH）这一名称。据报道，GH的存在与HP无关，而是与慢性活动性胃炎有关。我们描述了一名31岁男性上腹部症状患者的病例，该患者接受了食管胃十二指肠镜检查，结果显示十二指肠充血。胃体黏膜正常，未发现HP，而胃窦部发现了与HP相关的活动性慢性胃炎。此外，在该部位胃小凹内和黏液层下方观察到少数呈4 - 5个螺旋、比HP大的螺旋菌。该病例是我们所在地理区域（意大利南部）关于在人胃中发现不同于HP的细菌可能性的首例报告。同时存在的HP使我们无法将患者的慢性活动性胃炎与类GH细菌联系起来。然而，我们的发现提示了在B型胃窦部慢性炎症过程中HP和GH可能同时存在的可能性。此前的研究未观察到这种关联。
