钕钇铝石榴石激光治疗早期阴茎癌可保留阴茎的形态和功能。
Nd:YAG laser treatment of early stage carcinoma of the penis preserves form and function of penis.
作者信息
Tewari Mallika, Kumar Mohan, Shukla Hari S
机构信息
Department of Surgical Oncology, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India.
出版信息
Asian J Surg. 2007 Apr;30(2):126-30. doi: 10.1016/S1015-9584(09)60145-7.
INTRODUCTION
We analysed the results of penis-preserving (conservative) treatment of early stage cancer of the penis with neodymium: yttrium-aluminium-garnet (Nd:YAG) laser with long-term follow-up in a developing country.
METHODS
This was a retrospective study of 32 patients with cancer penis from 1993 to 2005 who were treated by Nd:YAG laser local excision and in situ coagulation of the tumour bed.
RESULTS
Out of 32 patients who were treated with Nd:YAG laser, 25 had (p)T(1) and seven had (p)T(2) stage cancer penis. The median follow-up was 70 months (range, 6-120 months). Two had stopped attending the follow-up clinic after 6-12 months. Three patients had concurrent and six had delayed inguinal block dissection. There was no mortality but two (6.25%) patients developed recurrence in 48-60 months post laser excision. Penis was preserved in all 32 patients. All patients were satisfied with the cosmetic result. Eight patients practiced celibacy, in 23 sexual functions were normal and in one this information was not available. Micturition was in standing posture in all 32 patients.
CONCLUSION
The result of this study shows that Nd:YAG laser treatment of early stage cancer penis has good local control with preservation of the penis.
引言
我们分析了在一个发展中国家对早期阴茎癌采用钕：钇铝石榴石（Nd:YAG）激光进行保留阴茎（保守）治疗并长期随访的结果。
方法
这是一项对1993年至2005年期间32例阴茎癌患者的回顾性研究，这些患者接受了Nd:YAG激光局部切除及肿瘤床原位凝固治疗。
结果
在接受Nd:YAG激光治疗的32例患者中，25例为（p）T（1）期，7例为（p）T（2）期阴茎癌。中位随访时间为70个月（范围6 - 120个月）。2例在6 - 12个月后停止到随访门诊就诊。3例患者同时进行了腹股沟淋巴结清扫，6例进行了延迟腹股沟淋巴结清扫。无死亡病例，但2例（6.25%）患者在激光切除后48 - 60个月出现复发。所有32例患者的阴茎均得以保留。所有患者对美容效果满意。8例患者禁欲，23例性功能正常，1例未提供此信息。所有32例患者排尿均为站立姿势。
结论
本研究结果表明，Nd:YAG激光治疗早期阴茎癌对局部控制良好，且能保留阴茎。
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