Chan Albert Chi-Yan, Lo Chung Mau, Ng Irene Oi-Lin, Fan Sheung Tat
Department of Surgery, The University of Hong Kong, Hong Kong SAR.
Asian J Surg. 2007 Apr;30(2):143-6. doi: 10.1016/S1015-9584(09)60149-4.
Combined hepatocellular cholangiocarcinoma (cHCC-CC) is an uncommon histological variant of primary liver cancer. This combined type of tumour lesion follows an aggressive clinical course with an unfavourable prognosis. Although the role of orthotopic liver transplantation in the management for hepatocellular carcinoma is well defined, to date, there has been no report on its treatment value for cHCC-CC. We report our experience of orthotopic liver transplantation in three patients with cHCC-CC. One patient succumbed to distant metastases 16.5 months after liver transplantation whereas the other two patients continued to survive 35 and 25 months after transplantation, respectively.
肝内胆管癌合并肝细胞癌（cHCC-CC）是原发性肝癌中一种罕见的组织学亚型。这种复合型肿瘤病变临床进程侵袭性强，预后不良。尽管原位肝移植在肝细胞癌治疗中的作用已明确，但迄今为止，尚无关于其对cHCC-CC治疗价值的报道。我们报告了3例cHCC-CC患者接受原位肝移植的经验。1例患者在肝移植后16.5个月死于远处转移，而另外2例患者分别在移植后35个月和25个月仍存活。
