Plotinsky Rachel N, Talbot Elizabeth A, Kellenberg Joan E, Reef Susan E, Buseman Sandra K, Wright Karen D, Modlin John F
Division of Public Health Services, Department of Health and Human Services, Concord, NH, USA.
Clin Pediatr (Phila). 2007 May;46(4):349-55. doi: 10.1177/0009922806293915.
We describe a case of congenital rubella syndrome with typical stigmata in an infant born in New Hampshire to Liberian refugees. The infant's clinical specimens were tested for rubella. Rubella immunity status was sought for contacts. The infant's specimen cultures grew wild-type rubella virus; serum immunoglobulin M and G were positive. Eighteen of 20 contacts were rubella-immune. Family's transit history, mother's vaccination history, and infant's estimated gestational age supported congenital infection acquired overseas. Clinicians should maintain vigilance for congenital rubella syndrome in infants with relevant stigmata, particularly those whose mothers are from countries with nonexistent or recently implemented rubella vaccination programs.
我们描述了一例先天性风疹综合征病例，患儿出生于新罕布什尔州，其父母为利比里亚难民，患儿有典型的病症体征。对该婴儿的临床样本进行了风疹检测。对其接触者的风疹免疫状况进行了调查。婴儿样本培养物中培养出野生型风疹病毒；血清免疫球蛋白M和G呈阳性。20名接触者中有18人对风疹免疫。患儿家庭的过境史、母亲的疫苗接种史以及婴儿的估计胎龄均支持在海外获得先天性感染的推断。临床医生应对有相关病症体征的婴儿，尤其是其母亲来自未实施或近期才实施风疹疫苗接种计划国家的婴儿，保持对先天性风疹综合征的警惕。
