Weinsaft Jonathan W, Klem Igor, Judd Robert M
Greenberg Division of Cardiology, Weill Medical College of Cornell University, 525 East 68th Street, Starr-4, New York, NY 10021, USA.
Cardiol Clin. 2007 Feb;25(1):35-56, v. doi: 10.1016/j.ccl.2007.02.001.
Accurate distinction between viable and infarcted myocardium is important for assessment of patients who have cardiac dysfunction. Through the technique of delayed-enhancement MRI (DE-MRI), viable and infarcted myocardium can be simultaneously identified in a manner that closely correlates with histopathology findings. This article provides an overview of experimental data establishing the physiologic basis of DE-MRI-evidenced hyperenhancement as a tissue-specific marker of myocardial infarction. Clinical data concerning the utility of transmural extent of hyperenhancement for predicting response to medical and revascularization therapy are reviewed. Studies directly comparing DE-MRI to other viability imaging techniques are presented, and emerging applications for DE-MRI are discussed.
准确区分存活心肌和梗死心肌对于评估心脏功能不全的患者至关重要。通过延迟强化磁共振成像（DE-MRI）技术，可以同时识别存活心肌和梗死心肌，其方式与组织病理学结果密切相关。本文概述了实验数据，这些数据确立了DE-MRI显示的强化作为心肌梗死组织特异性标志物的生理基础。回顾了关于强化透壁范围对预测药物治疗和血运重建治疗反应的效用的临床数据。介绍了直接将DE-MRI与其他存活心肌成像技术进行比较的研究，并讨论了DE-MRI的新兴应用。
