Prasher Deepak, Al-Hajjaj Haifa, Aylott Susan, Aksentijevic Aleksander
Ear Institute, University College, London, United Kingdom.
Noise Health. 2005 Oct-Dec;7(29):31-9. doi: 10.4103/1463-1741.31876.
Aircraft maintenance workers are exposed to a mixture of solvents in the presence of intermittent noise. For this study these workers exposed to solvent mix and noise, were compared with mill workers exposed to noise alone, printed circuit board operatives exposed to solvents alone and those exposed to none who acted as controls. Tympanometry, acoustic reflex thresholds, transient and distortion product otoacoustic emissions, auditory brainstem potentials, nystagmography and posturography were examined. There was a significant effect on pure tone thresholds for both noise and solvents+noise. The distortion product otoacoustic emissions declined with frequency and exhibited lower DP amplitude with noise compared to solvents and noise group. The transient emissions showed a similar effect. Over 32% of subjects with solvent and noise exposure had abnormalities of the auditory brainstem responses in terms of interwave interval prolongation. The mean acoustic reflex thresholds showed a pattern of differences which differentiate noise from solvent and noise groups. The contralateral pathway appears to be differentially affected by solvent exposure. 32% of subjects in the solvents and noise group had an abnormal posturographic finding. In the solvents and noise group 74% had abnormalities of saccades, 56% of pursuit and 45% of optokinetic nystagmus.
飞机维修工人在间歇性噪声环境中接触多种溶剂。在本研究中，将这些接触溶剂混合物和噪声的工人与仅接触噪声的工厂工人、仅接触溶剂的印刷电路板操作人员以及未接触任何物质的对照组人员进行了比较。对他们进行了鼓室图、声反射阈值、瞬态和畸变产物耳声发射、听觉脑干电位、眼震电图和姿势描记法检查。噪声和溶剂+噪声对纯音阈值均有显著影响。畸变产物耳声发射随频率下降，与溶剂和噪声组相比，噪声组的畸变产物耳声发射振幅更低。瞬态发射也显示出类似的效果。超过32%接触溶剂和噪声的受试者在听觉脑干反应方面存在波间期延长的异常。平均声反射阈值呈现出一种差异模式，可区分噪声组与溶剂和噪声组。对侧通路似乎受到溶剂暴露的不同影响。溶剂和噪声组中32%的受试者姿势描记法检查结果异常。在溶剂和噪声组中，74%的受试者扫视异常，56%的受试者跟踪异常，45%的受试者视动性眼震异常。
