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腹腔镜辅助下子宫颈闭锁和阴道发育不全患者的子宫前庭吻合术

Laparoscopically assisted uterovestibular anastomosis in patients with uterine cervix atresia and vaginal aplasia.

作者信息

Fedele Luigi, Bianchi Stefano, Frontino Giada, Berlanda Nicola, Montefusco Sarah, Borruto Franco

机构信息

Department of Obstetrics, Gynecology and Neonatology, Fondazione Policlinico-Mangiagalli-Regina Elena, University of Milan, Milan, Italy.

出版信息

Fertil Steril. 2008 Jan;89(1):212-6. doi: 10.1016/j.fertnstert.2007.01.168. Epub 2007 May 4.

Abstract

OBJECTIVE

To describe the surgical technique and the long-term anatomic and functional results of laparoscopically assisted uterovestibular anastomosis.

DESIGN

Descriptive study.

SETTING

Tertiary referral center.

PATIENT(S): Twelve consecutive patients with uterine cervix atresia and vaginal aplasia.

INTERVENTION(S): Laparoscopically assisted uterovestibular anastomosis was performed in all patients. Follow-up assessments at 1, 6, and 12 months included pelvic examination, transvaginal ultrasonography, and, in selected cases, vaginoscopy and hysteroscopy. Subsequent follow up was done by referring physicians or by means of telephone interview. Mean follow-up was 6 years.

MAIN OUTCOME MEASURE(S): Intra- and postoperative characteristics and anatomic and functional outcome.

RESULT(S): The surgical procedure was successful in all cases and all of the women have experienced regular menstruation. At 6-month follow-up, mean vaginal length was 6 cm and at least 80% of neovaginal epithelium was iodine-positive in all patients. Six women were sexually active during follow-up without difficulty. None have yet attempted to seek a pregnancy.

CONCLUSION(S): The study shows the safety and effectiveness of a laparoscopic approach to uterovestibular anastomosis in women with cervical atresia and vaginal aplasia. In these patients, we believe that conservative surgery should represent the first therapeutic option. A longer follow-up is needed to assess pregnancy rates and outcome.

摘要

目的

描述腹腔镜辅助子宫前庭吻合术的手术技术以及长期的解剖学和功能结果。

设计

描述性研究。

地点

三级转诊中心。

患者

12例连续性宫颈闭锁和阴道发育不全患者。

干预措施

所有患者均接受腹腔镜辅助子宫前庭吻合术。在1、6和12个月时进行随访评估,包括盆腔检查、经阴道超声检查,在特定病例中还包括阴道镜检查和宫腔镜检查。后续随访由转诊医生进行或通过电话访谈完成。平均随访时间为6年。

主要观察指标

术中和术后特征以及解剖学和功能结果。

结果

所有病例手术均成功,所有女性均有规律月经。在6个月随访时,平均阴道长度为6cm,所有患者中至少80%的新阴道上皮碘染色阳性。6名女性在随访期间有性生活且无困难。尚无患者尝试怀孕。

结论

该研究表明腹腔镜辅助子宫前庭吻合术治疗宫颈闭锁和阴道发育不全女性的安全性和有效性。对于这些患者,我们认为保守手术应作为首选治疗方案。需要更长时间的随访来评估妊娠率和结局。

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