Wheeler Arthur P, Bernard Gordon R
Medical Intensive Care Unit, Vanderbilt University Medical Center, Nashville, TN 37232-2650, USA.
Division of Allergy, Pulmonary, and Critical Care Medicine, Vanderbilt University Medical Center, Nashville, TN 37232-2650, USA.
Lancet. 2007 May 5;369(9572):1553-1564. doi: 10.1016/S0140-6736(07)60604-7.
Acute respiratory distress syndrome and acute lung injury are well defined and readily recognised clinical disorders caused by many clinical insults to the lung or because of predispositions to lung injury. That this process is common in intensive care is well established. The mainstay of treatment for this disorder is provision of excellent supportive care since these patients are critically ill and frequently have coexisting conditions including sepsis and multiple organ failure. Refinements in ventilator and fluid management supported by data from prospective randomised trials have increased the methods available to effectively manage this disorder.
急性呼吸窘迫综合征和急性肺损伤是明确且易于识别的临床病症，由多种对肺部的临床损伤或肺部损伤易感性所致。这一过程在重症监护中很常见，这一点已得到充分证实。这种病症的主要治疗方法是提供优质的支持性护理，因为这些患者病情危重，且常常伴有包括败血症和多器官衰竭在内的并存病症。前瞻性随机试验数据支持下的呼吸机和液体管理的改进，增加了有效管理这种病症的可用方法。
