人类U13小核仁RNA的三个假基因属于III类。

Three pseudogenes for human U13 snRNA belong to class III.

作者信息

Baserga S J, Yang X D, Steitz J A

机构信息

Department of Molecular Biophysics and Biochemistry, Howard Hughes Medical Institute, Yale University School of Medicine, New Haven, CT 06510.

出版信息

Gene. 1991 Nov 15;107(2):347-8. doi: 10.1016/0378-1119(91)90340-h.

DOI:10.1016/0378-1119(91)90340-h

PMID:1748306

Abstract

The nucleotide sequences of three pseudogenes for the small nucleolar RNA, U13, were determined from three human DNA clones. The sequences are reported 50 bp 5' and 3' to each gene. These pseudogenes belong to class III because they contain dispersed mismatches when compared to the previously determined U13 RNA sequence, an adenine-rich region at the 3' end, and short imperfect repeats flanking the 5' end of the coding sequence and the 3' end of the adenine-rich region.

摘要

从小核仁RNA U13的三个假基因的核苷酸序列是从三个人类DNA克隆中测定的。这些序列报告了每个基因5'端和3'端的50个碱基对。这些假基因属于III类，因为与先前确定的U13 RNA序列相比，它们含有分散的错配、3'端的富含腺嘌呤区域，以及编码序列5'端和富含腺嘌呤区域3'端两侧的短不完全重复序列。