Lanting Brent, Athwal George S, Naudie Douglas D R
Schulich School of Medicine, University of Western Ontario, London, Ontario, Canada.
Clin Orthop Relat Res. 2007 Aug;461:20-4. doi: 10.1097/BLO.0b013e318073c273.
Clostridium perfringens is a rare, life-threatening infection. We present an atypical evolution of spontaneous Clostridium perfringens myonecrosis in a monitored healthy patient. After a head injury, the hemodynamically stable patient became febrile and grew cultures of Clostridium perfringens with no identifiable focus. Antibiotics were initiated. Seventy-two hours after culture results, the patient complained of shoulder pain and imaging revealed periscapular subcutaneous emphysema. Multiple surgical débridements of the necrotic supraspinatus muscle were required to eradicate the infection. The unique features of this patient include the opportunity to (1) follow the progression of clostridial myonecrosis in a healthy patient in a monitored setting and (2) study the extended period of time between positive cultures and the onset of clinical myonecrosis, a feature at odds with the classic rapid progression.
产气荚膜梭菌是一种罕见的、危及生命的感染。我们报告了一例在监测下的健康患者中自发性产气荚膜梭菌性肌坏死的非典型病程。一名头部受伤后血流动力学稳定的患者出现发热,培养出产气荚膜梭菌但未发现明确感染灶。开始使用抗生素治疗。培养结果出来72小时后,患者主诉肩部疼痛,影像学检查显示肩胛周围皮下气肿。为根除感染,需要对坏死的冈上肌进行多次手术清创。该患者的独特之处包括:(1)有机会在监测环境下观察健康患者中梭菌性肌坏死的进展情况;(2)研究阳性培养结果与临床肌坏死发作之间的较长时间间隔,这一特征与经典的快速进展情况不符。