Department of Plastic and Reconstructive Surgery, University of Rome Tor Vergata, Rome, ItalyRegenerative Surgery, University of Rome Tor Vergata, Rome, ItalyClinical Laboratory of Experimental Neurorehabilitation, Santa Lucia Foundation, I.R.C.C.S., Rome, Italy.
Int Wound J. 2014 Feb;11(1):93-7. doi: 10.1111/j.1742-481X.2012.01072.x. Epub 2012 Sep 13.
Clostridial myonecrosis (CM) is a rare, life threatening necrotizing infection of a skeletal muscle caused by Clostridium perfringens in the majority of cases. The diagnosis may be difficult because of few diagnostic and cutaneous signs early in its course. Standard therapy involves surgical debridements of a devitalized tissue and high-dose organism-specific antibiotic therapy. The hyperbaric oxygen has also showed its usefulness in the treatment of these infections. Autograft systems as tissue replacement, based on bioengineered materials, have been demonstrated to be safe and effective treatments for chronic wounds and a suitable physiotherapy is recommended for the recovery of functional impairments of upper extremities. We present a rare case of CM of right upper limb treated with a combination of standard treatments and new techniques.
梭菌性肌坏死(CM)是一种罕见的、危及生命的骨骼肌坏死性感染,由大多数情况下的产气荚膜梭菌引起。由于其病程早期的诊断和皮肤体征很少,因此诊断可能较为困难。标准治疗包括对失活组织进行手术清创和大剂量针对特定病原体的抗生素治疗。高压氧治疗也已显示出在这些感染中的有效性。基于生物工程材料的自体移植物系统已被证明是治疗慢性创伤的安全有效的方法,建议进行适当的物理治疗以恢复上肢的功能障碍。我们报告了一例罕见的右侧上肢 CM 病例,采用标准治疗联合新技术治疗。