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纤维蛋白胶(Tissucol)在腹腔镜保守治疗脾外伤中作为止血剂的应用。

Use of fibrin glue (Tissucol) as a hemostatic in laparoscopic conservative treatment of spleen trauma.

作者信息

Olmi S, Scaini A, Erba L, Bertolini A, Guaglio M, Croce E

机构信息

Department of General Surgery, Center of Laparoscopic and Minimally Invasive Surgery, Ospedale San Gerardo, Monza, Italy.

出版信息

Surg Endosc. 2007 Nov;21(11):2051-4. doi: 10.1007/s00464-007-9288-7. Epub 2007 May 5.

Abstract

BACKGROUND

This study aimed to evaluate the effect of fibrin glue in laparoscopic spleen-preserving procedures for traumatic rupture.

METHODS

From January 2002 to December 2005, six laparoscopic spleen-preserving procedures were performed for traumatic rupture using fibrin glue. Two of the cases had previous middle and lower abdominal surgery. Survey of the abdominal cavity was performed by inserting two 5- to 12-mm trocars, one 5-mm trocar, and a 30 degree scope. A complete survey of all the patients was performed.

RESULTS

None of the patients required laparotomy, and no postoperative bleeding occurred. The fibrin sealant achieved immediate hemostasis, and all the patients recovered without further splenic bleeding. The mean postoperative stay was 4.3 days (range, 4-5 days). All the patients were followed up for 3 to 12 months. Postoperative immunoglobulin scanning, ultrasonography, and computed tomography (CT) results were normal.

CONCLUSIONS

Laparoscopic management of spleen trauma can be used once a positive diagnosis has been made. It is useful for assessing the degree of splenic injury. A laparoscopic spleen-preserving procedure can be used safely for patients with stable vital data. It is an effective procedure for the evaluation and treatment of hemodynamically stable patients with splenic injuries for whom nonoperative treatment is controversial. The topical application of a fibrin sealant in splenic trauma achieves definitive hemostasis safely, rapidly, and reliably. It also is simple to use in either laparoscopic or open procedures.

摘要

背景

本研究旨在评估纤维蛋白胶在腹腔镜保脾治疗外伤性脾破裂手术中的作用。

方法

2002年1月至2005年12月,采用纤维蛋白胶对6例外伤性脾破裂患者实施腹腔镜保脾手术。其中2例患者既往有中下腹部手术史。通过插入两个5至12毫米的套管针、一个5毫米套管针和一个30度的腹腔镜对腹腔进行探查。对所有患者进行了全面检查。

结果

所有患者均无需开腹手术,术后无出血发生。纤维蛋白封闭剂实现了即时止血,所有患者均康复,未再发生脾出血。术后平均住院时间为4.3天(范围4 - 5天)。所有患者均随访3至12个月。术后免疫球蛋白扫描、超声检查及计算机断层扫描(CT)结果均正常。

结论

一旦确诊,腹腔镜治疗脾外伤即可应用。它有助于评估脾损伤程度。对于生命体征稳定的患者,腹腔镜保脾手术可安全实施。对于非手术治疗存在争议的血流动力学稳定的脾损伤患者,这是一种有效的评估和治疗方法。在脾外伤中局部应用纤维蛋白封闭剂可安全、快速、可靠地实现确切止血。它在腹腔镜手术或开放手术中使用都很简便。

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