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帕拉金糖对大鼠外翻肠葡萄糖吸收的抑制作用。

Inhibitory effect of palatinose on glucose absorption in everted rat gut.

作者信息

Kashimura Jun, Nagai Yukie

机构信息

Research Laboratory, Mitsui Sugar Co., Ltd., Honson 1-2-14, Chigasaki, Kanagawa 253-0042, Japan.

出版信息

J Nutr Sci Vitaminol (Tokyo). 2007 Feb;53(1):87-9. doi: 10.3177/jnsv.53.87.

DOI:10.3177/jnsv.53.87
PMID:17484386
Abstract

We previously reported that the increase in blood glucose was more suppressed when palatinose was taken with sucrose or glucose than when either of these sugars was taken alone. In the present study, we examined whether or not palatinose suppresses glucose absorption using everted intestinal sacs from rats. Glucose absorption in the everted rat intestinal sac was measured with 0, 1, 2.5 or 5 mM of palatinose added to 20 mM glucose. The measurement was repeated five times for each palatinose level to calculate a mean value. The result showed glucose absorption to be reduced as the palatinose level increased. It was significantly reduced when 5 mM palatinose was added as compared with no palatinose addition (p<0.05). These results suggest that palatinose suppresses glucose absorption.

摘要

我们之前报道过,与单独摄入蔗糖或葡萄糖相比,将帕拉金糖与蔗糖或葡萄糖一起摄入时,血糖的升高受到了更大程度的抑制。在本研究中,我们使用大鼠的外翻肠囊来检测帕拉金糖是否会抑制葡萄糖吸收。在添加了0、1、2.5或5 mM帕拉金糖的20 mM葡萄糖溶液中测量大鼠外翻肠囊的葡萄糖吸收情况。每个帕拉金糖水平重复测量5次以计算平均值。结果表明,随着帕拉金糖水平的升高,葡萄糖吸收减少。与不添加帕拉金糖相比,添加5 mM帕拉金糖时葡萄糖吸收显著降低(p<0.05)。这些结果表明帕拉金糖会抑制葡萄糖吸收。

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