Min Jin-Young, Min Kyung-Bok, Paek DoMyung, Cho Sung-Il
School of Public Health and Institute of Health and Environment, Seoul National University, Seoul, Republic of Korea.
J Clin Densitom. 2007 Apr-Jun;10(2):184-8. doi: 10.1016/j.jocd.2006.12.004. Epub 2007 Feb 16.
Although bone mineral density (BMD) measurements of peripheral bone have been widely used due to practical and economic factors, a consensus does not exist as to whether the dominant or nondominant side is preferable for diagnosing osteoporosis and predicting fracture risk. Thus, we evaluated BMD differences of the distal radius and calcaneus between dominant and nondominant sides in the Korean population. Data were collected from 1794 subjects (979 females and 815 males) aged 4-86 yr, who were not taking any medication that affected bone metabolism or had a history of fracture. All subjects completed a questionnaire, and anthropometric and BMD measurements were taken. BMD values at the distal radii and calcanei were measured by dual-energy X-ray absorptiometry using a Lunar instrument. Significant correlations were observed between the dominant and nondominant distal radii (r=0.92; p<0.0001) and calcanei (r=0.94; p<0.0001). A side difference for the distal radius was not observed, whereas a significant side difference for the calcaneus was detected (p<0.05). Our findings provide information for recommending a sampling site upon measuring the distal radius and calcaneus during clinical or community-based studies.
尽管由于实际和经济因素，外周骨骨密度（BMD）测量已被广泛应用，但对于优势侧还是非优势侧更适合用于诊断骨质疏松症和预测骨折风险，目前尚无共识。因此，我们评估了韩国人群中优势侧和非优势侧桡骨远端和跟骨的骨密度差异。数据收集自1794名年龄在4至86岁之间的受试者（979名女性和815名男性），这些受试者未服用任何影响骨代谢的药物，也没有骨折史。所有受试者均完成了一份问卷，并进行了人体测量和骨密度测量。使用Lunar仪器通过双能X线吸收法测量桡骨远端和跟骨的骨密度值。优势侧和非优势侧桡骨远端（r = 0.92；p < 0.0001）以及跟骨（r = 0.94；p < 0.0001）之间观察到显著相关性。未观察到桡骨远端的侧别差异，而检测到跟骨存在显著的侧别差异（p < 0.05）。我们的研究结果为在临床或社区研究中测量桡骨远端和跟骨时推荐采样部位提供了信息。
