Department of Epidemiology, School of Public Health, Institute of Health and Environment, Seoul National University, Seoul, Republic of Korea.
J Bone Miner Metab. 2010;28(1):94-100. doi: 10.1007/s00774-009-0110-6. Epub 2009 Jul 28.
This study evaluated age-related changes in bone mineral density (BMD) and identified the peak bone mineral density (PBMD) in Koreans. We recruited 2929 subjects, ranging in age from 5 to 86 years, from three regions: Seoul, Siwha, and Gwangyang. The BMD at the distal radius and calcaneus were measured with dual-energy X-ray absorptiometry, and anthropometric measures were also obtained. PBMD was calculated from the highest mean in each age group. The PBMD at the distal radius was 0.514 +/- 0.06 g/cm(2) in females and 0.598 +/- 0.07 g/cm(2) in males. Peak ages for both sexes were the thirties. For the calcaneus, PBMD was 0.509 +/- 0.09 g/cm(2) in females and 0.629 +/- 0.09 g/cm(2) in males. Peak ages were the thirties for females and the twenties for males. These results could facilitate international or interracial comparisons and be used as reference data to screen for osteoporosis in Koreans.
本研究评估了韩国人骨密度(BMD)随年龄的变化,并确定了峰值骨密度(PBMD)。我们招募了来自首尔、泗和、光阳三个地区的 2929 名年龄在 5 至 86 岁之间的受试者。采用双能 X 射线吸收法测量桡骨远端和跟骨的 BMD,并获得人体测量学指标。PBMD 是根据每个年龄组的最高平均值计算得出的。女性桡骨远端 PBMD 为 0.514 +/- 0.06 g/cm(2),男性为 0.598 +/- 0.07 g/cm(2)。男女的峰值年龄均为三十多岁。对于跟骨,女性 PBMD 为 0.509 +/- 0.09 g/cm(2),男性为 0.629 +/- 0.09 g/cm(2)。女性的峰值年龄为三十多岁,男性为二十多岁。这些结果有助于进行国际或种族间比较,并可作为筛查韩国人骨质疏松症的参考数据。