Lahiri Anindya, Waters R
Birmingham University Hospitals, Birmingham, UK.
J Plast Reconstr Aesthet Surg. 2007;60(6):663-7. doi: 10.1016/j.bjps.2006.07.010. Epub 2007 Feb 9.
Bio-Alcamid (Polymekon, Italy) is a relatively new, injectable soft tissue endoprosthesis that is recommended for correcting soft tissue defects and contour deformities. It consists of 96% water and 4% synthetic polymeric polyalkylimide, and once injected becomes enclosed within a thin collagen capsule.
We have treated a selected series -- 34 patients, 57 anatomical sites treated in 64 treatment sessions, with a range of 2.5 ml to 110 ml injected per site per injection. The indications have been as diverse as anti-retrovirus treatment associated facial lipoatrophy, pectus excavatum and post-breast reconstruction contour deformities. The patients were followed up in clinics and through a postal questionnaire survey.
The longest follow up we have now is over eighteen months. The results have been uniformly good and satisfactory to both patients and the surgeon. The patients tolerated the treatment very well under local anaesthesia. The questionnaire survey showed universally high degrees of satisfaction. The biggest advantages of Bio-Alcamid over other filler injections have been permanency of volume correction and a very natural soft feel of the treated areas. Many patients required a single treatment only to correct significant volume defects.
In our experience, Bio-Alcamid is safe and fulfils most of the criteria of an ideal injectable filler material.
Bio-Alcamid（意大利波利梅孔公司）是一种相对新型的可注射软组织假体，推荐用于矫正软组织缺损和轮廓畸形。它由96%的水和4%的合成聚合物聚烷基酰亚胺组成，注射后会被包裹在一层薄薄的胶原囊中。
我们选取了一组患者——34例，共64个治疗疗程，治疗了57个解剖部位，每个部位每次注射量为2.5毫升至110毫升。适应症多种多样，包括抗逆转录病毒治疗相关的面部脂肪萎缩、漏斗胸和乳房重建后的轮廓畸形。通过门诊随访和邮寄问卷调查对患者进行跟踪。
我们目前最长的随访时间超过了18个月。结果一直良好，患者和外科医生都很满意。患者在局部麻醉下对治疗耐受性良好。问卷调查显示普遍满意度很高。Bio-Alcamid相对于其他填充剂注射的最大优势在于体积矫正的永久性以及治疗区域非常自然的柔软触感。许多患者仅需单次治疗就能矫正明显的体积缺损。
根据我们的经验，Bio-Alcamid是安全的，并且满足理想可注射填充材料的大多数标准。
