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幽门螺杆菌感染与胃癌的发病率:一项基于医院的8年研究。

Incidence of helicobacter pylori infection and gastric cancer : an 8-year hospital based study.

作者信息

Saragih J Boas, Akbar Nurul, Syam Ari Fahrial, Sirait S, Himawan Sutisna, Soetjahyo E

机构信息

Department of Internal Medicine, Faculty of Medicine, Indonesian Christian University/Endoscopy Unit, Cikini Christian Communion of Churches in Indonesia Hospital, Jakarta, Indonesia.

出版信息

Acta Med Indones. 2007 Apr-Jun;39(2):79-81.

PMID:17485791
Abstract

AIM

To observe the tendency of decreased prevalence of H pylori infection in a 14 year-period and observe the prevalence of intestinal metaplasia and gastric cancer.

METHODS

All patients who were diagnosed with dyspepsia and underwent esophagogastroduodenoscopy in Cikini hospital Jakarta from January 1998 until December 2005 were evaluated. We evaluated the histopathologic result of H pylori, the presence of intestinal metaplasia and gastric cancer. Data was grouped for 1 year period of time and was presented descriptively.

RESULTS

Decreased prevalence of H. Pylori infection was found, from 12.8% in 1998, 12.4% in 1999, 14.7% in 2000, 9.6% in 2001, 11.9 % in 2002, 3.8% in 2003, 2.3% in 2004, 2.9% in 2005. Intestinal metaplasia was 4.7% in 1998, 3.2% in 1999, 3.1% in 2000, 2.3 % in 2001, 7.6% in 2002, 8.3% in year 2003, 6.5% in 2004, 7.1% in 2005. Prevalence of gastric cancer was 2.2% in 1998, 0.25% in 1999, 1.1% in 2000, 1.1% in 2001, 1.1% in 2002, 1.8% in 2003, 1.7% in 2004, 3.9% in 2005.

CONCLUSION

There was decreased prevalence of H pylori infection in 8 year-period but there was no decreased prevalence of intestinal metaplasia and gastric cancer found.

摘要

目的

观察14年间幽门螺杆菌感染率下降的趋势,并观察肠化生和胃癌的患病率。

方法

对1998年1月至2005年12月在雅加达奇基尼医院被诊断为消化不良并接受食管胃十二指肠镜检查的所有患者进行评估。我们评估了幽门螺杆菌的组织病理学结果、肠化生和胃癌的存在情况。数据按1年时间段分组并进行描述性呈现。

结果

发现幽门螺杆菌感染率下降,1998年为12.8%,1999年为12.4%,2000年为14.7%,2001年为9.6%,2002年为11.9%,2003年为3.8%,2004年为2.3%,2005年为2.9%。肠化生在1998年为4.7%,1999年为3.2%,2000年为3.1%,2001年为2.3%,2002年为7.6%,2003年为8.3%,2004年为6.5%,2005年为7.1%。胃癌患病率在1998年为2.2%,1999年为0.25%,2000年为1.1%,2001年为1.1%,2002年为1.1%,2003年为1.8%,2004年为1.7%,2005年为3.9%。

结论

8年间幽门螺杆菌感染率有所下降,但未发现肠化生和胃癌的患病率下降。

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