与晚期艾滋病相关的产后发病率。
Postpartum morbidity associated with advanced HIV disease.
作者信息
Louis Judette, Buhari Mudathiru A, Allen Dianne, Gonik Bernard, Jones Theodore B
机构信息
Department of Obstetrics and Gynecology, Division of Maternal Fetal Medicine, Wayne State University, Detroit, MI 48201, USA.
出版信息
Infect Dis Obstet Gynecol. 2006;2006:79512. doi: 10.1155/IDOG/2006/79512.
OBJECTIVE
To investigate the postpartum morbidity and postpartum management of febrile morbidity associated with advanced HIV infection.
METHODS
A case control study of HIV infected women at a tertiary care center during January 2000-June 2005 was performed. Postpartum morbidity was defined as endometritis, blood transfusion, wound complication, readmission, infectious morbidity, or unexpected surgery.
RESULTS
Women in Group 1 had AIDS (N=33), Group 2 were relatively immunocompetent HIV infected women (N=115), and Group 3 were uninfected women (N=152). Group 1 was more likely to have a postpartum morbidity (32.3 versus 19.3 and 13.2%, P=.03) and to have postpartum imaging 18.8 versus 7.9 and 2.6%, P=.002. After controlling for potential confounders, cesarean delivery (OR 6.2, 95% CI 2.1-505.5) but not advanced HIV disease was associated with an increased risk of postpartum morbidity.
CONCLUSION
Cesarean delivery and not advanced HIV disease increases the risk of postpartum morbidity in women with AIDS.
目的
探讨晚期HIV感染相关的产后发病率及发热性疾病的产后管理。
方法
对2000年1月至2005年6月期间在一家三级护理中心的HIV感染女性进行病例对照研究。产后发病率定义为子宫内膜炎、输血、伤口并发症、再次入院、感染性疾病或意外手术。
结果
第1组为患有艾滋病的女性（N = 33），第2组为免疫功能相对正常的HIV感染女性（N = 115），第3组为未感染女性（N = 152）。第1组发生产后发病的可能性更高（32.3% 对比19.3%和13.2%，P = 0.03），且进行产后影像学检查的比例更高（18.8% 对比7.9%和2.6%，P = 0.002）。在控制潜在混杂因素后，剖宫产（比值比6.2，95%置信区间2.1 - 505.5）而非晚期HIV疾病与产后发病风险增加相关。
结论
剖宫产而非晚期HIV疾病增加了艾滋病女性产后发病的风险。
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