Rodríguez-Bonfante Claudina, Amaro Aned, García María, Mejías Wohlert Ligia Elena, Guillen Pamela, Antonio García Rafael, Alvarez Naysan, Díaz Marialejandra, Cárdenas Elsys, Castillo Silvia, Bonfante-Garrido Rafael, Bonfante-Cabarcas Rafael
Decanato de Medicina, Universidad Centroccidental Lisandro Alvarado, Barquisimeto, Venezuela.
Cad Saude Publica. 2007 May;23(5):1133-40. doi: 10.1590/s0102-311x2007000500015.
A seroepidemiological survey and vector captures were performed in four rural communities in Andrés Eloy Blanco, Lara State, Venezuela. Systematic random sampling was based on family clusters, with samples drawn from 869 individuals to determine anti-Trypanosoma cruzi and anti-Leishmania sp. antibodies by indirect immunofluorescence. Positive individuals were defined as > or = 1:32 for anti-T. cruzi antibody and non-reactive to Leishmania sp. antigen, revealing an antibody frequency of 6.9% (n = 60), of whom 46.66% were females and 53.33% males and 60% were over 39 years of age. Some 5 (8.33%) seropositive individuals were under 10 years of age and 10 (16.66%) under 20 years. Rhodnius prolixus and Panstrongylus geniculatus were the triatomines captured, with infestation rates of 1.9% and 10.54%, colonization index of 0% and 18.18% in infested houses, and a T. cruzi infection index of 20% and 5.07%, respectively. The results suggest active Chagas disease transmission in Andrés Eloy Blanco in the last two decades and that P. geniculatus is replacing R. prolixus as the Chagas disease vector.
在委内瑞拉拉腊州安德烈斯·埃洛伊·布兰科的四个农村社区开展了血清流行病学调查并进行了病媒捕获。系统随机抽样以家庭群组为基础，从869个人中抽取样本，通过间接免疫荧光法测定抗克氏锥虫和抗利什曼原虫属抗体。抗克氏锥虫抗体阳性个体定义为≥1:32，且对利什曼原虫属抗原无反应，抗体频率为6.9%（n = 60），其中46.66%为女性，53.33%为男性，60%年龄超过39岁。约5名（8.33%）血清阳性个体年龄在10岁以下，10名（16.66%）年龄在20岁以下。捕获的锥蝽为长红锥蝽和膝状锥蝽，侵扰率分别为1.9%和10.54%，在受侵扰房屋中的定殖指数分别为0%和18.18%，克氏锥虫感染指数分别为20%和5.07%。结果表明，在过去二十年中安德烈斯·埃洛伊·布兰科存在活跃的恰加斯病传播，且膝状锥蝽正在取代长红锥蝽成为恰加斯病病媒。
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